Tag: urinary tract infection (UTI)

1. No significant difference in severe UTIs was observed between patients starting SGLT-2 inhibitors for type 2 diabetes, compared to DPP-4 inhibitors or GLP-1 agonists. Evidence Rating Level: 2 (Good) Study Rundown: The sodium glucose cotransporter-2 (SGLT-2) inhibitors are a newer class of diabetic medications that act by inhibiting glucose reabsorption in...
Efficacy of prehospital criteria in identifying trauma patients susceptible to undertriage While the early recognition of severe traumatic injury is associated with improved morbidity and mortality, undertriage has been associated with poorer patient outcomes. Previous research has shown that tachypnea and blunt thoracic injury are associated with undertriage. In this...
1. No significant difference in severe UTIs was observed between patients starting SGLT-2 inhibitors for type 2 diabetes, compared to DPP-4 inhibitors or GLP-1 agonists. Evidence Rating Level: 2 (Good) Study Rundown: The sodium glucose cotransporter-2 (SGLT-2) inhibitors are a newer class of diabetic medications that act by inhibiting glucose reabsorption...
Urinary tract infection (UTI) is the most common bacterial infection in elderly patients, and the spectrum of illness ranges from mild and self-limiting to severe urosepsis. More evidence is needed to determine the ideal initial management of UTI in the primary care setting. In this retrospective cohort study, 312,896...
Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results Cervical artery dissection is a common cause of ischemic stroke in young patients. Whether antiplatelet (AP) therapy or anticoagulation (AC) therapy is more effective at preventing recurrent stroke...
1. In this randomized controlled trial, women with uncomplicated urinary tract infections receiving 5-days of nitrofurantoin experienced increased clinical and microbiologic resolution at 28 days compared to single-dose fosfomycin. 2. Adverse events were rare, mostly gastrointestinal, and not significantly different between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Use of nitrofurantoin...
1. In this randomized controlled trial, meropenem-vaborbactam was found to be non-inferior to piperacillin-tazobactam for treating complicated urinary tract infections (UTIs). 2. The rate of adverse events were similar between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: As carbapenemases become more prevalent among organisms that cause complicated Urinary Tract Infections (UTIs),...
1. Urinalysis had ≥90% sensitivity and specificity in identifying urinary tract infection (UTI) among infants ≤60 days old with fever, regardless of presence of associated bacteremia. 2. Sensitivity of urinalysis was slightly higher among infants with associated bacteremia compared to those without, however specificity remained constant. Study Rundown: UTI is a...
1. Proportion of children ≤60 days old receiving more than 4 days (long-course) of intravenous (IV) antibiotics for urinary tract infection (UTI) decreased from 2005 to 2015 without an associated increase in readmission rates. 2. Female sex, younger age, and non-Hispanic white ethnicity were associated with higher rates of 30-day...
1. In this national implementation project involving community-based nursing homes, implementation of technical and socioadaptive bundles, which included training for catheter care and aseptic insertion, removal guidelines, regular assessments, resident and family engagement, and effective communication, significantly reduced the rates of catheter-associated urinary tract infections. 2. Catheter utilization did not...