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EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... ↑ Try EvidencePulse™ Ask the evidence.
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#VisualAbstract: Higher Nicotine Consumption Observed Among Youth with Attention-Deficit-Hyperactivity Disorder

byAngel GaoandAlisha Yi
April 16, 2025
in StudyGraphics
Reading Time: 2 mins read
#VisualAbstract: Higher Nicotine Consumption Observed Among Youth with Attention-Deficit-Hyperactivity Disorder
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1. This cohort of United States youths with asymptomatic attention-deficit hyperactivity disorder (ADHD), did not have statistically significant differences in their odds of starting nicotine or tobacco products compared with the control group. 

2. The youths with more ADHD symptoms had a greater likelihood of starting nicotine or tobacco products compared to the control group.

Evidence Rating Level: 2 (Good)

Study Rundown: Tobacco use is the leading cause of preventable death worldwide. The relationship between tobacco and attention-deficit/hyperactivity disorder (ADHD) has been well established although changing over time. Features of ADHD include functional impairment, lack of attention, and possibly hyperactivity. This cohort study aimed to find additional research regarding the association between tobacco use and ADHD. Included in the cohort were children aged 12 to 17 years old along with their parents, from baseline in September 2013 to April 2023. The key outcome of interest was the new onset of 4 nicotine or tobacco use among youths who reported no lifetime use at baseline. The parent participants reported if their child had been diagnosed with ADHD or ADD, and if so, were they taking regular medication. The youth completed questions from the Global Appraisal of Individual Needs (GAIN) assessment including a list of symptoms listed on the PhenX Toolkit. When compared to the control group, individuals with asymptomatic ADHD did not significantly differ in the likelihood of initiating cigarette use, dual use, or other tobacco use throughout the study period. On the other hand, youth with symptomatic ADHD had a greater chance of starting nicotine or tobacco products during the study period. This study included individuals 12 years of age and older, however, some youths had already initiated nicotine or tobacco by this age. Future research should aim to evaluate ADHD symptoms corresponding with nicotine and tobacco use earlier. Overall, the study findings highlight the importance of early ADHD diagnosis and treatment in youths to prevent future nicotine and tobacco use.

Click here to read the study in JAMA Network Open

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EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... ↑ Try EvidencePulse™ Ask the evidence.
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