Nerandomilast slows decline in FVC in idiopathic pulmonary fibrosis
1. In this randomized trial, among patients with idiopathic pulmonary fibrosis (IPF), nerandomilast slowed the decline in the forced vital...
Mazdutide significantly reduces weight in adults with overweight or obesity
1. In this randomized controlled trial, weekly administration of Mazdutide resulted in significant weight reduction in adults classified as overweight...
Inebilizumab improves outcome in patients generalized myasthenia gravis
1. In patients with myasthenia gravis (MG) who had anti-acetylcholine receptor antibodies or anti-muscle-specific kinase antibodies, intravenous inebilizumab reduced disease...
Structured exercise intervention improves survival in colon cancer patients
1. In this randomized controlled trial, patients with resected stage III or high-risk stage II colon cancer who completed adjuvant...
Cerebral embolic protection does not decrease stroke incidence in TAVI patients
1. In this randomized trial, the use of cerebral embolic protection (CEP) did not decrease the 72-hour incidence of stroke...
Nerandomilast slows FVC decline in progressive pulmonary fibrosis
1. In this randomized controlled trial, treatment with nerandomilast led to slower declines in forced vital capacity (FVC) in patients...
AAV gene therapy shows durable benefit in hemophilia B
1. In this prospective cohort study, a single intravenous dose of scAAV2/8-LP1-hFIXco gene therapy in men with severe hemophilia B...
Tumor-infiltrating clonal hematopoiesis is associated with NSCLC recurrence
1. In this retrospective cohort study, the presence of tumor-infiltrating clonal hematopoiesis (TI-CH) was associated with an increased risk of...
Upadacitinib with glucocorticoids superior to glucocorticoids alone for giant cell arteritis remission
1. In this randomized trial, upadacitinib dosed at 15mg with a 26-week glucocorticoid taper showed superior efficacy than placebo with...
Trimethoprim-sulfamethoxazole during pregnancy does not reduce risk of prematurity
1. In this randomized controlled trial, prophylactic treatment with trimethoprim-sulfamethoxazole (TMP-SMX) was not associated with a reduction in the incidence...
