Patisiran is effective in treatment of hereditary transthyretin amyloidosis.
1. Patisiran, an RNA interference agent, improved neuropathy symptoms and motor function in patients with hereditary transthyretin amyloidosis after 18...
Lack of superiority of rivaroxaban for secondary prevention of embolic stroke of undetermined source
1. At a median follow-up of eleven months, rivaroxaban was not superior to aspirin for prevention of secondary stroke after...
MRI pattern selects patients with unknown stroke time who benefit from thrombolysis
1. Stroke patients with unknown time of stroke onset and DWI-FLAIR mismatch indicative of a stroke within the prior 4.5...
Cannabidiol plus conventional antiepileptics reduces drop seizure frequency in the Lennox-Gastaut syndrome
1. Amongst adults and children with the Lennox-Gastaut (LG) syndrome, addition of cannabidiol to a conventional antiepileptic regimen reduced drop...
EXTEND-IA TNK: Tenecteplase is superior to alteplase as neoadjuvant treatment for mechanical thrombectomy
1. When treated with tenecteplase, stroke patients eligible for mechanical thrombectomy had higher rates of reperfusion and superior clinical outcomes...
![Galangin may sensitize apoptosis-resistant renal carcinoma cells [PreClinical]](https://www.2minutemedicine.com/wp-content/uploads/2016/01/Papillary_renal_cell_carcinoma_-_very_high_mag-350x250.jpg)
Nivolumab plus ipilimumab improve survival in advanced renal cell carcinoma
1. Amongst patients with advanced renal-cell carcinoma and an intermediate or poor prognosis, nivolumab plus ipilimumab was superior to sunitinib...
Flucytosine plus fluconazole is noninferior to amphotericin B in treating cryptococcal meningitis
1. Treatment of cryptococcal meningitis with two weeks of flucytosine and fluconazole was noninferior to two weeks of amphotericin B....
No effect of crystalloid type on in-hospital death and length of stay in non-critically ill patients
1. Patients treated with either balanced crystalloids or normal saline did not differ in number of hospital-free days alive after...
No benefit of sodium bicarbonate or acetylcysteine for prevention of complications after angiography: The PRESERVE trial
1. Amongst patients undergoing angiography, neither sodium bicarbonate nor acetylcysteine were effective in preventing a composite outcome of death, need...
Mogamulizumab is safe and possibly effective in HTLV-1-associated myelopathy
1. In this combined phase 1-2a study, mogamulizumab used for treatment of human T-lymphotropic virus type 1 (HTLV-1) associated myelopathy...