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Troponin T levels may be a predictor of mortality in diabetes and heart disease patients: BAR 2D Trial
1. Patients with abnormal troponin T levels had a significantly higher rate of death from all causes at the 5-year...
Inhibition of apoliprotein lowers triglyceride levels
1. ISIS 304801 is an antisense oligonucleotide that targets APOC3 mRNA to decrease plasma levels of APOC3. 2. Patients...
Endovascular repair of AAA provides perioperative benefits but long-term survival similar to open repair
1. Patients who underwent endovascular repair of abdominal aortic aneurysms (AAA) had lower perioperative mortality than those who received an...
The addition of liraglutide to diet and exercise leads to increased weight loss
1. For overweight and obese patients, the addition of liraglutide once daily to a diet and exercise regimen resulted in...
Ibrutinib effective for previously treated Waldenström’s macroglobulinemia
1. Ibrutinib, an inhibitor of Bruton’s tyrosine kinase, produced a response in 90.5% of patients with Waldenström’s macroglobulinemia. 2. Patient...
Mass treatment with azithromycin may be effective in eradicating yaws
1. Mass treatment with single-dose azithromycin was successful in decreasing the prevalence of active and latent yaws. Evidence Rating Level:...
Deaths of extremely premature infants decrease, necrotizing enterocolitis deaths on the rise
1. From 2000 to 2011, the overall mortality of extremely premature infants decreased. 2. Death attributed to pulmonary and infectious...
![Combo angiotensin-neprilysin inhibitor superior to enalapril in heart failure [PARADIGM-HF trial]](https://2minutemedicine-wpengine.netdna-ssl.com/wp-content/uploads/2014/09/Angiotensin-350x250.jpg)
Combo angiotensin-neprilysin inhibitor superior to enalapril in heart failure [PARADIGM-HF trial]
1. LCZ696 is a novel drug that combines the neprilysin inhibitor, sacubitril, and the angiotensin receptor blocker (ARB), valsartan. 2....
Infusion of CCR5-modified autologous CD4 T cells safe for HIV patients
Image: PD 1. Transfer of autologous CD4 T cells, with genome editing of the CCR5 gene, to HIV patients was...
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