• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

CABG associated with decreased mortality compared to stenting in diabetic patients

byJeffrey CampbellandSai Folmsbee
November 17, 2014
in Cardiology, Chronic Disease, Endocrinology
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

1. According to a meta-analysis of coronary revascularization techniques in diabetics, coronary artery bypass grafting (CABG) was associated with decreased mortality rates compared to percutaneous coronary interventions (PCI).

2. CABG was associated with higher risk of strokes than PCI.

Evidence Rating Level: 1 (Excellent) 

Study Rundown: Cardiac disease is the most common cause of death among diabetics, and diabetics form a large proportion of patients who undergo coronary artery revascularization each year. Despite the substantial research regarding the use of stents to open narrowed arteries or bypass grafting to divert bloodflow, the best revascularization method remains unclear in diabetic patients. This study analyzed results from trials comparing percutaneous coronary interventions (PCI) with coronary artery bypass grafting (CABG) specifically in patients with diabetes. When data from these trials were combined in a meta-analysis, CABG was found to be associated with decreased mortality rates compared to PCI, as well as a decrease in a composite outcome of mortality, heart attack and stroke in patients with diabetes. Notably, when risk of stroke was analyzed separately from mortality and heart attacks, CABG was found to be associated with increased risk of stroke compared to PCI. Although this study incorporated results from several trials, a single, large trial may have highly influenced the results of the analysis, potentially limiting the strength of the results. Nevertheless, the analysis confirms prior results suggesting that CABG is associated with improved mortality outcomes compared to PCI in diabetic patients.

Click to read the study, published today in Annals of Internal Medicine

Relevant Reading: Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies

In-Depth [systematic review and meta-analysis]: This network meta-analysis examined results from 40 trials evaluating revascularization procedures in diabetics with angina and multivessel or left main coronary artery disease. Included studies compared either bare metal stents (PCI-BMS) or drug eluting stents (PCI-DES) with CABG, or compared PCI-BMS with PCI-DES to establish the analysis. The network meta-analysis approach, incorporating evidence on the relationship between PCI-BMS and PCI-DES, facilitated analysis of studies that took place over a number of years during which both CABG and PCI procedures evolved, and during which PCI transitioned from reliance upon BMS to frequent use of DES. Overall, compared to CABG, PCI was found to be associated with mildly increased odds of a combined mortality/myocardial infarction/stroke endpoint (OR 1.33; 95%CrI 1.01–1.65) and mortality (OR 1.44; 95%CrI 1.05–1.91), but decreased odds of stroke (OR 0.56; 95%CrI 0.38–0.88). Despite these results, the decreased odds of stroke associated with PCI highlights the continued need for individualized clinical judgment when recommending revascularization procedures for patients with diabetes.

RELATED REPORTS

Unmarried status associated with an increased risk of mortality in Asian populations

#VisualAbstract: CT associated with lower complication risks than invasive coronary angiography

Mediterranean diet superior to low-fat diet in secondary prevention of cardiovascular events

More from this author: Atrial fibrillation likely increases risk of silent strokes HIV rebound observed after therapeutic stem cell transplant USPSTF recommends behavioral counseling to reduce cardiovascular disease ACP recommends non-pharmacologic treatment of urinary incontinence in women Corticosteroids and physical therapy equally effective for shoulder impingement syndrome

Image: PD

©2014 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. No article should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2 Minute Medicine, Inc.

Tags: Coronary artery diseaserevascularization
Previous Post

Cardiac biomarkers unnecessarily ordered in emergency departments

Next Post

Hyperbaric oxygen does not significantly improve post-concussion symptoms

RelatedReports

Parents desensitized with increasing exposure to movie violence/sex
Cardiology

Unmarried status associated with an increased risk of mortality in Asian populations

June 1, 2022
#VisualAbstract: CT associated with lower complication risks than invasive coronary angiography
StudyGraphics

#VisualAbstract: CT associated with lower complication risks than invasive coronary angiography

June 1, 2022
FDA-approved weight loss medications associated with weight loss at one year
Cardiology

Mediterranean diet superior to low-fat diet in secondary prevention of cardiovascular events

May 25, 2022
SARS-CoV-2 is associated with higher incidence of Kawasaki disease in children
Cardiology

Systematic review of Kawasaki disease shows excellent long-term survival

February 9, 2022
Next Post
Hyperbaric oxygen does not significantly improve post-concussion symptoms

Hyperbaric oxygen does not significantly improve post-concussion symptoms

Unclear if medical therapy management improves health outcomes

Unclear if medical therapy management improves health outcomes

NSAIDs linked with serious bleeding in afib patients

NSAIDs linked with serious bleeding in afib patients

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Management of uncomplicated urinary tract infections amongst women in the United States Military Health System highly concordant with guidelines
  • Gout flares associated with a transient increase in subsequent risk of cardiovascular events
  • Litifilimab associated with reduced disease severity in patients with cutaneous lupus erythematosus
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.