• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI EvidencePulse™
  • Pharma
  • AI News
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI EvidencePulse™
  • Pharma
  • AI News
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Cardiovascular medications may improve outcomes for patients with type 2 myocardial infarction

byKathleen LauandAlex Chan
January 4, 2021
in Cardiology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Although infrequently prescribed, treatment with cardiovascular medications in patients with type 2 myocardial infarction (T2MI) and acute or chronic myocardial injury may lower mortality risk.

Evidence Rating Level:  2 (Good)

While patients with non-ischemic myocardial injury and type 2 myocardial infarction (T2MI) are associated with poorer outcomes and higher mortality, compared to patients with type 1 myocardial infarction (T1MI), there is ongoing debate regarding their treatment. Specifically, whether cardiovascular medications used in T1MI treatment would improve clinical outcomes in patients with other types of myocardial injury remains unknown. In this observational cohort study, records from 3 893 patients (mean age 73 years), taken from the Swedish National Patient Register, presenting with chest pain at the Karolinska University Hospital in Stockholm and with a discharge diagnosis of MI, were evaluated. Participants were divided into cohorts with T2MI, non-ischemic acute myocardial injury, and T1MI. They were then categorized according to the number of cardiovascular medications, calculated from all prescriptions dispensed within 180 days of their emergency department visit: those taking 0-1, 2-3, and 4 medications. Patients with T2MI and chronic myocardial injury were infrequently prescribed cardiovascular medications. For instance, approximately 15% of patients with T2MI and chronic myocardial injury did not receive any type of studied medicine (including ACEi, ARB, platelet inhibitors, and B-Blockers), such as only 40% of patients in these cohorts being given statins, compared to 87% of patients with T1MI.  With a mean follow-up of 3.1+ 1.5 years, 27% of patients died, with yearly mortality rates decreasing with increasing numbers of medications across all types of myocardial injury. For example, patients with T2MI treated with 2-3 and 4 medications were associated with 50% (aHR 0.50, NSD) and 56% (0.43, 95% CI 0.19-0.96) lower rates of mortality than those taking 0-1 medications. These findings support a more generous approach to prescribing cardiovascular medications in patients with T2MI and acute or chronic myocardial injury may reap mortality benefit. However, this study was limited by its observational methods, lack of additional patient history to eliminate residual confounders, and its small number of patients and events in certain analyses (i.e. only 8 deaths in the reference group). Future studies should clarify diagnoses by accessing coronary angiographies and stress tests, and explore the effect of prescribed doses of specific medications.

Click to read the study in JAHA

Image: PD

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

RELATED REPORTS

β-Blocker Use and Health Status Among Patients With Heart Failure With Preserved Ejection Fraction

An absence of cardiovascular risk factors is linked to over ten additional healthy years

2 Minute Medicine Rewind September 1, 2025

Tags: acute myocardial infarctioncardiology
Previous Post

2 Minute Medicine Rewind January 3, 2021

Next Post

#VisualAbstract: Special Report: Vaccines in Development- Johnson & Johnson vaccine as another frontrunner

RelatedReports

Long-term outcomes for off-pump and on-pump CABG are similar
Cardiology

β-Blocker Use and Health Status Among Patients With Heart Failure With Preserved Ejection Fraction

September 5, 2025
Cardiology

An absence of cardiovascular risk factors is linked to over ten additional healthy years

September 2, 2025
Imatinib safe and effective as long-term treatment for chronic myeloid leukemia: The IRIS trial
Weekly Rewinds

2 Minute Medicine Rewind September 1, 2025

September 1, 2025
Cardiology

Significant body weight reduction with cagrilintide-semaglutide therapy

August 29, 2025
Next Post
#VisualAbstract: Cabotegravir plus rilpivirine given every 8 weeks is non-inferior to every 4 weeks for maintenance of HIV-1 viral suppression

#VisualAbstract: Special Report: Vaccines in Development- Johnson & Johnson vaccine as another frontrunner

Intensive rehabilitation not superior to traditional therapy for arm function after stroke

Occult blood in feces is associated with an increased risk of ischemic stroke and myocardial infarction

#VisualAbstract: Cabotegravir plus rilpivirine given every 8 weeks is non-inferior to every 4 weeks for maintenance of HIV-1 viral suppression

#VisualAbstract: Use of inhaled corticosteroids is not associated with improved COVID-related mortality in patients with chronic respiratory conditions

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • β-Blocker Use and Health Status Among Patients With Heart Failure With Preserved Ejection Fraction
  • Leqembi gains at home injection for maintenance dosing
  • Computed Tomographic Angiography and Yield for Gastrointestinal Bleeding in the Emergency Department
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2025 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI EvidencePulse™
  • Pharma
  • AI News
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2025 2 Minute Medicine, Inc. - Physician-written medical news.