• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Occult blood in feces is associated with an increased risk of ischemic stroke and myocardial infarction

byKathleen LauandAlex Chan
January 5, 2021
in Cardiology, Neurology, Surgery
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

RELATED REPORTS

CYP2C19 loss-of-function carriers have modest benefit from ticagrelor and aspirin following cerebrovascular event: CHANCE-2 Trial

The EAST-AFNET 4 trial: Early rhythm control therapy for atrial fibrillation [Classics Series]

2 Minute Medicine Rewind June 13, 2022 

1. Positive fecal immunochemical test (FIT) results were associated with increased incidences of ischemic stroke, myocardial infarction, and all-cause mortality.

Evidence Rating Level: 2 (Good)

While fecal immunochemical tests (FIT) is a commonly used and effective screening tool for colorectal cancer (CRC), their clinical use in detecting other diseases is poorly known. As cardiovascular diseases and CRCs share risk factors such as old age, smoking, and physical inactivity, these conditions may share an underlying pathogenesis (i.e. systemic inflammation). Therefore, FIT results may share some insight into cardiovascular morbidity and all-cause mortality. In this nationwide population-based cohort study, 6 277 446 participants (over 50 years old) with CRC screening records from 2009-2012 in the South Korean National Health Insurance database were included. Patients with a history of cardiovascular disease and/or CRC were excluded. Over a median follow-up of 6.79 years, incidence rates of both ischemic stroke (4.88 vs 3.90 per 1000 patient years) and myocardial infarction (2.99 vs 2.44 per 1000 patient years) were higher in the FIT-positive over the FIT-negative group. This increased risk of ischemic stroke (aHR 1.25, 95%CI 1.23-1.27) and MI (aHR 1.09, 95% CI 1.19-1.25) remained significant after adjusting for demographic, social history, and comorbidity factors. Additionally, FIT-positive results were associated with increased all-cause mortality (aHR 1.15, 95% CI 1.07-1.23). Furthermore, these associated risks remained positive regardless of CRC and/or anemia status. By demonstrating an association between FIT positivity and increased stroke, MI, and all-cause mortality, these findings support a role for FIT beyond CRC screening. Nonetheless, randomized controlled trials would be needed to establish any causal relationships; future studies should also evaluate antithrombotic use, a common cause of false positive FIT results, and be capable of distinguishing between first-time and recurrent cardiovascular events.

Click to read the study in JAHA

Image: PD

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: cardiologyFecal Occultneurologystroke
Previous Post

#VisualAbstract: Special Report: Vaccines in Development- Johnson & Johnson vaccine as another frontrunner

Next Post

#VisualAbstract: Use of inhaled corticosteroids is not associated with improved COVID-related mortality in patients with chronic respiratory conditions

RelatedReports

Intensive rehabilitation not superior to traditional therapy for arm function after stroke
Chronic Disease

CYP2C19 loss-of-function carriers have modest benefit from ticagrelor and aspirin following cerebrovascular event: CHANCE-2 Trial

June 23, 2022
The ABCD2 score: Risk of stroke after Transient Ischemic Attack (TIA) [Classics Series]
Cardiology Classics

The EAST-AFNET 4 trial: Early rhythm control therapy for atrial fibrillation [Classics Series]

June 13, 2022
Long-term outcomes for off-pump and on-pump CABG are similar
Weekly Rewinds

2 Minute Medicine Rewind June 13, 2022 

June 20, 2022
Weekly Rewinds

2 Minute Medicine Rewind June 6, 2022

June 6, 2022
Next Post
#VisualAbstract: Cabotegravir plus rilpivirine given every 8 weeks is non-inferior to every 4 weeks for maintenance of HIV-1 viral suppression

#VisualAbstract: Use of inhaled corticosteroids is not associated with improved COVID-related mortality in patients with chronic respiratory conditions

Being overweight and obese associated with increased incidence of chronic kidney disease

Outcomes associated with discontinuation of RASi in patients with chronic kidney disease

#VisualAbstract: Total body skin examinations may aid in the detection of incidental skin cancers in patients with suspicious lesions

#VisualAbstract: Total body skin examinations may aid in the detection of incidental skin cancers in patients with suspicious lesions

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Intravenous fluid restriction does not improve septic shock outcomes
  • Intravenous vitamin C increases mortality and organ dysfunction in sepsis patients
  • Magnetic resonance based preoperative evaluation for perianal fistulas superior to traditional clinical method and improve surgical outcomes [Classics Series]
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.