Tag: neurology

Effect of screen time on recovery from concussion 1. In a single-center trial, decreased screen time during an acute concussion recovery period shortened the duration of concussive symptoms in a pediatric population.  Evidence Rating Level: 1 (Excellent)  Children and adolescents have the highest incidence of concussion, comprising many visits to the emergency...
Evidence Rating Level: 2 (Good) 1. Transdermal cannabidiol gel was found to be a safe and effective treatment for children and adolescents with developmental and epileptic encephalopathies  2. Treatment with transdermal cannabidiol was associated with a reduction in focal impaired awareness seizures and tonic-clonic seizures. Developmental and epileptics encephalopathies (DEEs)...
1. Vasoactive intestinal polypeptide may play a key role in the mechanism of migraine pathogenesis. 2. Drug therapies targeting vasoactive intestinal polypeptide receptors may be beneficial for treating migraines. Evidence Rating Level:  1 (Excellent) The pathophysiology of migraines is an intricate and complex process that is not yet fully understood. However, it...
Association between self-reported importance of religious or spiritual beliefs and end-of-life care preferences among people receiving dialysis 1. Religious and spiritual beliefs of dialysis patients had an impact on their end-of-life care planning and resuscitation preferences. 2. An integrative approach to end-of-life care that takes into consideration patients’ religious and spiritual...
1. For mild traumatic brain injury, various pathological findings were associated with different prognostic implications for mild traumatic brain injury up to 1 year.  Evidence Rating Level: 2 (Good) An acute traumatic brain injury (TBI) is characterized by various forms of intracranial hemorrhage observed on a computed tomography (CT) scan. The...
Real time remote symptom monitoring during chemotherapy for cancer: European multicentre randomised controlled trial (eSMART) 1. A daily remote symptom monitoring system reduced both the physical and psychological burden of chemotherapy side effects across six chemotherapy cycles, compared to standard care. Evidence Rating Level: 1 (Excellent) Individuals undergoing chemotherapy can experience numerous...
1. Among patients receiving deep brain stimulation for Parkinson’s disease, a home health management program was found to be safe, feasible, and significantly reduced the need for traditional clinic management. Evidence Rating Level: 1 (Excellent) Study Rundown: Deep brain stimulation (DBS) has shown to be effective in the management of...
1. In a cohort of extremely premature infants, high screen time contributes to adverse cognitive, executive function, and behavioural outcomes at ages 6 to 7. Evidence Rating Level: 2 (Good) Increased screen time is known to be negatively associated with cognitive development and executive function. Similarly, children who are born...
Accuracy of tau positron emission tomography as a prognostic marker in preclinical and prodromal Alzheimer disease 1. Tau PET predicted cognitive change and effect sizes were greater than amyloid PET and MRI. 2. MRI mediated the association between tau PET and cognition among Alzheimer’s and amyloid-positive MCI groups. Evidence Rating...
Relation of severe COVID-19 in Scotland to transmission-related factors and risk conditions eligible for shielding support: REACT-SCOT case-control study 1. Very high risk individuals that qualified for shielding interventions from COVID-19 were still at elevated risk for developing a severe infection. 2. Recent hospital exposures were the greatest risk factor for...