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Lilly’s retatrutide achieves significant weight loss and A1C reduction in Phase 3 trial
1. Retatrutide met all major Phase 3 endpoints, delivering substantial reductions in both A1C and body weight in patients with...
Cardiology
Reports of high-impact cardiology studies by medical professionals
Early surgical valve replacement offers survival benefit in asymptomatic, very severe aortic stenosis
1. This randomized controlled trial involving subjects with asymptomatic, very severe aortic stenosis demonstrated that over a ten-year period, early...
Atopic dermatitis activity is not associated with cardiovascular risk
1. In this cohort study, more active or severe atopic dermatitis (AD) in children was not associated with a greater...
Apixaban outperforms rivaroxaban in venous thromboembolism bleeding risk
1. In the randomized COBRRA trial, apixaban was associated with substantially less clinically relevant bleeding than rivaroxaban in patients with...
Placental abruption during pregnancy is not associated with increased risk of cardiovascular mortality in children
1. In this cohort of singleton offspring, placental abruption during pregnancy was associated with significantly increased risk of cardiovascular mortality...
New guidelines limit hypertension treatment in adults over 65
1. In this cross-sectional study, 11.4% of adults aged 65 years or older with untreated stage 1 hypertension, predominantly women...
Higher sleep apnea-specific hypoxic burden may predict postoperative cardiovascular complications and mortality in obstructive sleep apnea
1. In this cohort of patients with Obstructive sleep apnea (OSA), a higher sleep apnea-specific hypoxic burden (SASHB) was associated...
Lifestyle factors including higher body mass index and smoking are associated with changes in left-atrial size and function
1. In this prospective cohort study, lifestyle behaviours, especially higher body mass index (BMI) and smoking, are associated with measurable...
Replacing sedentary time with physical activity may lower risk of all-cause mortality
1. In this prospective cohort, individuals with greater periods of sedentary time have increased risks of all-cause mortality and mortality...
Adults with attention-deficit/hyperactivity disorder are at higher risk of poor long-term adherence to antihypertensive therapy
1. Adults with attention-deficit/hyperactivity disorder are more likely to discontinue antihypertensive therapy and demonstrate poor long-term adherence. 2. Use of...
