2 Minute Medicine Rewind April 21 – April 27, 2014

Image: PD In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. High versus Low Blood-Pressure...

Lorazepam not superior to diazepam for pediatric status epilepticus

Image: PD 1. Lorazepam did not significantly improve odds of status epilepticus cessation compared to diazepam.  2. Diazepam and lorazepam groups demonstrated similar rates of required...

Higher blood pressure targets in sepsis did not reduce mortality

Image: PD/CDC/Brower  1. In patients with septic shock, maintaining a higher mean arterial pressure (MAP) target of 80 to 85 mmHg did not have an...

Ambulances equipped for thrombolysis allow for more rapid stroke treatment

Image: PD  1. Ambulances equipped to give tissue plasminogen activator (tPA) for ischemic stroke allowed for more rapid treatment and increased rates of treatment.  2. Seven-day...

2 Minute Medicine Rewind April 7 – April 14, 2014

Image: PD In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Ledipasvir and Sofosbuvir for...

Childhood sexual abuse associated with later suicide attempts

Image: PD 1. Childhood sexual abuse is associated with an increased risk of suicide attempts. 2. The magnitude of the association between suicide attempt and childhood...

Increased incidence of stroke found after aortic valve replacement

Image: PD  1. Rates of clinical stroke after aortic valve replacement surgery were found to be 17%, more than twice the rate of 7% reported...

Fibrinolysis for pulmonary embolism may prevent hemodynamic collapse [PEITHO trial]

Image: CC/Heilman 1. Fibrinolysis in addition to standard anticoagulation reduced hemodynamic decompensation, but did not affect overall mortality, in patients with intermediate-risk pulmonary embolism.   2. Fibrinolysis...

QI methods improve adherence to PALS sepsis guidelines

Image: PD 1. Quality improvement (QI) methodology improved adherence to national pediatric sepsis guidelines and was sustained during the study period. 2. After the QI intervention...

Restrictive red blood cell transfusion may decrease risk of infection

Image: PD  1. Transfusion protocols employing restrictive transfusion thresholds demonstrate a decreased risk of infection as compared to those employing morel liberal thresholds.  2. Thirty-eight patients...
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