39·0°C versus 38·5°C ear temperature as fever limit in children with neutropenia undergoing chemotherapy...

1. In children with neutropenia and chemotherapy for cancer, 39·0°C ear temperature as a threshold for fever is non-inferior to 38·5°C for safety and...

Lower doses of ketamine shown to be non-inferior for acute pain control in the...

1. For the treatment of acute pain in the emergency setting, 0.15 mg/kg IV ketamine was shown to be non-inferior to a higher dose...

Tocilizumab may improve survival in COVID-19 patients with hypoxia and systemic inflammation 

1. Compared to usual care, fewer patients in the tocilizumab group died within 28 days of randomization. 2. Patients allocated tocilizumab were more likely to...

Health care workers working on COVID-19 wards at increased risk for nosocomial SARS-CoV-2 infection

1. The risk of SARS-CoV-2 infection was nearly 4-fold higher among health care workers working on COVID-19 inpatient wards compared to workers not in...

AAP recommends disaster preparedness measures for children

1. Given the unique medical, psychological, and developmental needs of children, the American Academy of Pediatrics (AAP) has issued a policy statement with pediatric-specific...

No difference between therapeutic hypo- and normo-thermia with in-hospital cardiac arrest in children

1. In children who suffered in-hospital cardiac arrest, there was no significant difference in 1-year survival in those randomized to a therapeutic hypothermia group...

Updated review confirms efficacy and safety of most standard treatments for latent tuberculosis infection

1. Results of a meta-analysis confirm evidence of efficacy and safety of 6-month isoniazid monotherapy and rifampicin monotherapy for latent tuberculosis infection treatment. 2. Combination...

Rising price of health services drove increase in US health care spending

1. This ecological study found that between 1996-2013, annual US health care spending was largely related to increases in health care service price and...

Greater rates of mortality linked to infants at risk for maltreatment

Infants classified as very high risk for substantiated maltreatment had a higher relative risk of overall mortality, death through unintentional and inflicted injury, and...

Significant variation in mortality trends in substance use disorders among US counties

1. Mortality rates decreased for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014. 2. Mortality rates for drug use disorders increased both...

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