Gastroenterology

Reports of high-impact gastroenterology studies by medical professionals

Tofacitinib effective as induction and maintenance therapy for ulcerative colitis

1. Patients with active ulcerative colitis who failed prior treatment achieved significantly greater remission of disease and mucosal healing compared to those treated with...

Oral neonatal rotavirus vaccine RV3-BB effective in preventing severe gastroenteritis

1. Newborns receiving the oral human neonatal rotavirus vaccine (RV3-BB) with the first dose occurring either at birth or at 8 weeks experienced fewer...

Quick Take: Histopathologic Predictors of Survival and Recurrence in Resected Ampullary Adenocarcinoma: International Multicenter...

Ampullary adenocarcinoma, arising at the ampulla of Vater in the duodenum, is a gastrointestinal malignancy often treated with surgical resection with curative intent. However,...

Quick Take: Liver Fibrosis and Metabolic Alterations in Adults with Alpha1 Antitrypsin Deficiency Caused...

Alpha-1 antitrypsin (AAT) is a major protease inhibitor responsible for the inhibition of neutrophil elastase and proteinase 3. Alpha-1 antitrypsin deficiency (AATD) is a...

Rectal indomethacin dose escalation for prevention of pancreatitis after endoscopic retrograde cholangiopancreatography in high-risk...

1. Dose escalation of rectal indomethacin does not provide any benefit in preventing pancreatitis in high-risk patients post-endoscopic retrograde cholangiopancreatography. Evidence Rating Level: 1 (Excellent) Pancreatitis...

Picky eaters more likely to display psychiatric impairment

1. Children who were identified as moderate or severe selective eaters (picky eaters) were more likely to display of psychopathological symptoms such as anxiety,...

Obeticholic acid associated with improved PBC biomarker trends compared to ursodiol: The POISE trial

1. Obeticholic acid therapy in patients with primary biliary cholangitis (PBC) associated with significantly greater decreases in alkaline phosphatase (ALP) and total bilirubin over...

Combination treatment with calcineurin inhibitors and IL-2 enhances transplant survival [PreClinical]

1. Blood from liver transplant patients treated with a calcineurin inhibitor (CNI) showed increased levels of apoptotic regulatory T cells (Tregs) and lower IL-2...

Patients with advanced adenomas are at increased risk of developing colorectal cancer

1. Patients with advanced adenomas identified on flex sigmoidoscopy had a significantly increased risk of death from colorectal cancer (CRC) compared to those with...

Aspirin therapy combined with warfarin without clinical indication associated with increased bleeding

1. In this retrospective cohort study conducted in Michigan, aspirin therapy combined with warfarin for patients without a clinical indication was associated with increased...
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