Peginesatide is noninferior to epoetin for anemia in hemodialysis patients [EMERALD Trials]
1. Hemodialysis patients who received peginesatide had similar hemoglobin levels and similar rates of adverse events as patients who received traditional epoetin treatments.
Published today...
Tolvaptan, a vasopressin receptor 2 antagonist, shows promise in polycystic kidney disease (TEMPO trial)
Image: PD/CDC. Cystic kidneys, gross pathology.
1. Tolvaptan can slow progression of autosomal dominant polycystic kidney disease both in terms of kidney volume and kidney function.
2....
The ALTITUDE trial: Aliskiren increases the risk of adverse events and stroke without any...
Image: CC
Key study points:
There was no difference in the incidence of primary outcomes (cardiovascular death, cardiac arrest with resuscitation, nonfatal MI, nonfatal stroke, etc.)...
A simple, cost-effective test for monitoring lupus nephritis
Image: CC. Lupus nephritis
Key findings:
The spot protein:creatinine ratio, a reproducible, cost-effective, and elegant test, correlates well with the labourious 24-hour urinary total protein excretion...
Gastric bypass surgery for the severely obese associated with higher diabetes remission versus nonsurgical...
Image: CC/MilitaryHealth
Key study points:
1. Patients undergoing Roux-en-Y gastric bypass surgery for severe obesity had higher rates of diabetes remission and lower risk of cardiovascular...
[BMJ] Kidney stones associated with increased risk of end-stage renal disease
Image: CC/James Heilman. Stone in kidney (arrow), CT scan.
Primer: Kidney stones are a commonly encountered clinical problem, and while there is limited evidence linking...
[THE LANCET] Severe chronic kidney disease patients have higher coronary risk than diabetics. Time...
Image: CC/PD. Enlarged kidney (drawing).
Primer: Coronary heart disease (CHD) “equivalent”, a term used to describe some trait or factor that results in a 10-year risk...
