Budesonide may be effective for slowing renal function decline in patients with IgA nephropathy
1. Reduction in time-weighted glomerular filtration rate (GFR) decline was significantly greater in Nefecon versus placebo. 2. Majority of adverse...
Nephrology
Reports of high-impact nephrology studies by medical professionals
Acute kidney injury more prevalent amongst extremely premature neonates
1. A secondary analysis of a randomized clinical trial found that when correcting for fluid balance, AKI was more commonly diagnosed...
Atezolizumab added to cabozantinib does not improve clinical outcomes in patients with metastatic renal cell carcinoma
1. Progression-free and overall survival was comparable in both the intervention and control groups. 2. Serious adverse events were more...
Risk of adverse kidney-related events for patients on lithium is low but increases with greater exposure
1. For patients newly initiated on lithium or valproate, the absolute risks of chronic kidney disease (CKD) progression or acute...
There is a low risk of chronic kidney disease progression following acute kidney injury
1. In this prospective cohort study, there was a limited association between acute kidney injury (AKI) and worsening kidney function...
Comparison between hydroxychloroquine and systemic corticosteroids in IgA nephropathy
1. For patients with IgA nephropathy (IgAN), long-term use of hydroxychloroquine demonstrated antiproteinuric effects compared to corticosteroids at 24 months. ...
Non-alcoholic fatty liver disease worsens cardiovascular outcomes in patients with kidney disease
1. In patients with CKD, non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiovascular events (CVE),...
Sparsentan superior to irbesartan for reduction of proteinuria in patients with IgA nephropathy
1. Patients in sparsentan group reported a 50% reduction in proteinuria compared to 15% in the irbesartan group at week...
Shorter antibiotic therapy courses likely noninferior in the treatment of complicated urinary tract infections and bacteremia
1. In bacteremic patients with complicated UTI, a 10-day course of typical antibiotics or a 7-day course of IV beta-lactams...
Intradialytic exercise may improve patient survival rates in patients receiving hemodialysis
1. Intradialytic exercise for a minimum of 60 minutes during thrice weekly dialysis sessions improved survival rates in adult patients...
