Weighted vests and resistance training confer similar outcomes for bone density in the elderly
1. In this 12-month randomized clinical trial, weight loss (WL)-associated bone loss occurred in older adults with obesity, regardless of...
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Breast cancer survivors may have a lower risk of Alzheimer’s dementia
1. In this retrospective cohort study, breast cancer survivors had a lower risk of Alzheimer’s dementia compared with cancer-free controls. ...
Evaluating scar outcomes in pediatric burn patients following skin grafting
1. In this cohort of pediatric burn patients, poorer long-term scar outcomes, as indicated by Patient and Observer Scar Assessment...
Novel inhibitory antibody, MAR001, lowers triglycerides and remnant cholesterol in humans
1. ANGPTL4 inhibition decreased triglyceride and remnant cholesterol levels by over 50%. 2. MAR001 was well-tolerated with no significant treatment-related...
Food compounds associated with disease activity in inflammatory bowel disease
1. This retrospective cohort study identified several dietary compounds, specifically fatty acids, that are associated with remission in inflammatory bowel...
Abbreviated MRI is superior to whole-breast ultrasound for detection of cancer in dense breasts
1. Abbreviated MRI detected three times as many invasive cancers compared with ABUS. 2. Contrast-enhanced mammography detected a greater number...
Volumetric diet and time-restricted eating demonstrate similar outcomes for weight reduction
1. In this randomized controlled trial comparing the volumetrics diet (VD) and time-restricted eating (TRE), both interventions led to significant...
Tirzepatide-associated improvements in cardiometabolic risk factors linked to degree of weight loss
1. In this post-hoc analysis of the SURMOUNT-1 trial, there was a mostly linear relationship between percentage change in weight...
Tarlatamab in Small-Cell Lung Cancer after Platinum-Based Chemotherapy
1. Median overall survival was 13.6 months in the tarlatamab group and 8.3 months in the chemotherapy group, with HR...
Reductions in pain catastrophizing are associated with improvements in emotional functioning
1. Reductions in pain catastrophizing are more closely associated with improvements in emotional functioning than with pain intensity Evidence Rating...