The POET trial: oral antibiotics in stable endocarditis patients noninferior to intravenous treatment
1. Patients with left sided infective endocarditis who switched to oral antibiotics once stable had similar composite adverse event outcomes compared to patients treated...
EEG-guided anesthetic administration unlikely to reduce post-operative delirium
1. In this randomized controlled trial, EEG-guided anesthetic administration during surgical interventions did not reduce the incidence of delirium compared to anesthetic administration as...
The OVIVA trial: oral antibiotics noninferior to intravenous antibiotics for bone and joint infections
1. Patients with bone and joint infections treated with 6 weeks of oral or intravenous antibiotic therapy had similar rates of treatment failure after...
Quick Take: Accelerated hypofractionated radiation therapy for elderly frail bladder cancer patients unfit for...
The standard of care for T2-T4aN0M0 muscle-invasive bladder cancer (MIBC) and high-risk non-MIBC in fit patients is radical cystectomy (RC). In patients unfit for...
Contemporary trends and outcomes of liver transplants for alcohol-associated liver disease
1. In this study of short and long-term outcomes of liver transplants in the United States, the proportion of transplants performed for alcohol-associated liver...
Quick Take: Use of Hormone Replacement Therapy and Risk of Venous Thromboembolism: Nested Case-Control...
Hormone replacement therapy (HRT), often prescribed to women during menopause, has been shown to increase the risk for venous thromboembolism (VTE). However, the effects...
Quick Take: Risk Prediction Tools to Improve Patient Selection for Carotid Endarterectomy Among Patients...
Risk Prediction Tools to Improve Patient Selection for Carotid Endarterectomy Among Patients with Asymptomatic Carotid StenosisCarotid endarterectomy (CEA) is an effective tool for revascularization...
Quick Take: Histopathologic Predictors of Survival and Recurrence in Resected Ampullary Adenocarcinoma: International Multicenter...
Ampullary adenocarcinoma, arising at the ampulla of Vater in the duodenum, is a gastrointestinal malignancy often treated with surgical resection with curative intent. However,...
Fecal microbiota transplantation improves remission rates in ulcerative colitis
1. In this randomized controlled trial, patients who received a donor fecal microbiota transplant (FMT) had a higher rate of steroid-free remission at 8-weeks...
The REGROUP trial: endoscopic and open vein-graft harvest associated with similar outcomes
1. Among patients randomized to an open or endoscopic vein-graft harvest technique for coronary-artery bypass graft (CABG) surgery, there was no difference in major...
