Kidney failure risk equation (KFRE) discriminates risk in children with chronic kidney disease
1. The kidney failure risk equation (KFRE), currently used in adults to estimate risk for progression to end-stage renal disease (ESRD) based on demographic...
Biennial biopsies may be adequate for men under active surveillance for prostate cancer
1. After accounting for differences in surveillance protocols and treatments, researchers found that estimates of risk for biopsy Gleason score (GS) upgrade were not...
Tolvaptan reduces eGFR decline in patients with polycystic kidney disease
1. Estimated glomerular filtration rate (eGFR) declined less over one year of treatment for patients with later-stage autosomal dominant polycystic kidney disease (ADPKD) taking...
Re-analysis of evidence suggests that PSA screening significantly reduces the risk for death from...
1. PSA screening was associated with a reduction in risk for death from prostate cancer.2. No differences in the effects of PSA screening were...
Canagliflozin reduces cardiovascular outcomes in patients with diabetes: The CANVAS
1. Canagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, significantly reduced the risk of the primary composite outcome of cardiovascular death, nonfatal myocardial infarction,...
Osteoporosis medications may improve bone health in men receiving androgen deprivation therapy for prostate...
1. Bisphosphonates and denosumab increased bone mineral density (BMD) in men receiving androgen deprivation therapy (ADT) for nonmetastatic prostate cancer, with denosumab also showing...
Despite adverse events, corticosteroids may benefit patients with IgA nephropathy
1. In this multicenter, double blind study, IgA nephropathy patients had improved kidney function with corticosteroid treatment compared to those treated with placebo.2. Unfortunately,...
Abiraterone associated with improved survival for advanced prostate cancer: The STAMPEDE trial
1. Men treated with abiraterone, prednisolone, and androgen-deprivation therapy (ADT) (combined therapy) demonstrated a significantly increased overall survival in comparison to those treated with...
More research needed to determine cardiovascular effects of long-term hormone therapy for transgender adults
1. Cross-sex hormone therapy (CSHT) may be associated with worsening cardiovascular risk factors in transgender men.2. CSHT may not result in increases in cardiovascular...
Electroacupuncture linked to improvements for stress urinary incontinence
1. Electroacupuncture was found to result in less urinary leakage for women with stress urinary incontinence compared to sham electroacupuncture after 6 weeks.Evidence Rating...
