General Medicine Classics

Physician-written reports of landmark medical studies

Classics Series, Landmark Trials in Medicine

The RACE-II trial: Lenient vs. strict rate-control in atrial fibrillation [Classics Series]

1. Lenient rate-control was found to be non-inferior to strict rate-control in managing patients with atrial fibrillation.2. Compared to strict rate-control, lenient rate-control could...
Classics Series, Landmark Trials in Medicine

The TRICC trial: Restrictive transfusion in intensive care does not increase mortality [Classics Series]

1. Using a restrictive transfusion strategy in critically ill patients did not significantly increase 30-day mortality when compared with a liberal transfusion strategy.2. Subgroup...
Classics Series, Landmark Trials in Medicine

The ACCORD trial: Intensive glucose control associated with increased mortality [Classics Series]

1. Previous studies suggest that intensive blood glucose control reduces the risk of microvascular complications, though questions remained regarding the impact on macrovascular complications...
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