![Adverse pregnancy outcomes associated with thrombophilias [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2015/07/Classics-2-Minute-Medicine-e1436017941513-350x250.png)
Delayed antimicrobial therapy linked with higher mortality in septic shock [Classics Series]
1. Septic shock is a complication of infection with very high mortality rates. 2. This study was one of the...
Emergency Classics
Physician-written reports of landmark emergency medicine studies
Prednisolone vs placebo in severe alcoholic hepatitis [Classics Series]
1. Compared to placebo, treating patients with severe alcoholic hepatitis with 28 days of prednisolone significantly improved the short-term survival...
The PROSEVA trial: Proning in severe ARDS [Classics Series]
1. In patients with severe acute respiratory distress syndrome (ARDS), prone-positioning significantly reduced 28-day and 90-day mortality when compared with...
The ACURASYS trial: Neuromuscular blockade in early ARDS [Classics Series]
1. In patients with severe acute respiratory distress syndrome (ARDS), treatment with neuromuscular blockade in the first 48 hours significantly...
Omeprazole versus placebo for bleeding peptic ulcer [Classics Series]
1. Patients presenting with upper gastrointestinal bleeds experienced significantly lower risk of continued bleeding and need for surgery to control...
Diffusion-weighted MRI highly sensitive, specific vs. CT in acute ischemic stroke [Classics Series]
1. Among patients with acute neurologic deficits presenting within six hours of symptoms onset, diffusion-weight magnetic resonance imaging (DWI) was...
The AMPLIFY trial: Apixaban for treatment of venous thromboembolism [Classics Series]
1. Apixaban was found to be non-inferior to conventional therapy (i.e., enoxaparin followed by warfarin) in the treatment of acute...
Vena caval filters in pulmonary embolism prophylaxis [Classics Series]
Image: PD 1. Permanent vena caval filter placement in addition to anticoagulant therapy helps prevent short-term occurrence of pulmonary embolism...
Albumin in cirrhotic patients with spontaneous bacterial peritonitis [Classics Series]
1. In cirrhotic patients with spontaneous bacterial peritonitis, albumin infusion on days 1 and 3 of treatment in addition to...
The OHTS trial: Topical ocular hypotensive medication reduces risk of open-angle glaucoma [Classics Series]
1. At 5 years, the probability of developing open-angle glaucoma was significantly lower in the group that received topical ocular...