![ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2013/05/web-cover-classics-with-logo-medicine-BW-small-jpg-350x250.jpg){kind=logo}
Ultrasound sensitive for appendicitis, improves outcomes [Classics Series]
1. Among patients with signs and symptoms consistent with acute appendicitis (AA), ultrasound demonstrated a sensitivity and specificity of 80%...
Emergency Classics
Physician-written reports of landmark emergency medicine studies
Canadian C-Spine Rules superior to NEXUS Low-Risk Criteria for detecting cervical-spine injuries [Classics Series]
1. The Canadian C-Spine Rule (CCR, Figure I) demonstrated higher sensitivity and specificity for cervical-spine injury compared to the National...
Ottawa ankle rules reduce the rate of referral for ankle radiography [Classics Series]
1. The Ottawa ankle rules significantly reduced referral for ankle, but not foot, radiography in the emergency department. 2. Patients...
Thrombectomy between 6 and 24 hours after acute stroke reduces disability: The DAWN trial [Classics Series]
1. Thrombectomy performed between 6 and 24 hours after onset of acute stroke in patients with a mismatch between stroke...
ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]
1. The ABCD2 score is a validated clinical tool that estimates the short-term risk of stroke following a transient ischemic...
The ACCORD trial: Intensive glucose control associated with increased mortality [Classics Series]
1. Previous studies suggest that intensive blood glucose control reduces the risk of microvascular complications, though questions remained regarding the...
![Adverse pregnancy outcomes associated with thrombophilias [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2015/07/Classics-2-Minute-Medicine-e1436017941513-350x250.png)
The ICAP trial: Colchicine in acute pericarditis [Classics Series]
1. Colchicine has been commonly used in the treatment of inflammatory conditions, including gout and serositis. 2. This study demonstrated...
The BHAT: Propranolol after acute myocardial infarction [Classics Series]
1. Beta-blockers were commonly used in the treatment of coronary artery disease in the 1980s, though prior studies were inconclusive...
The VALIANT trial: Valsartan vs. captopril in patients with acute myocardial infarction and heart failure [Classic Series]
1. In patients with acute myocardial infarction and heart failure/evidence of left ventricular dysfunction, patients treated with valsartan and captopril...
Ceftriaxone vs. norfloxacin for prophylaxis in patients with cirrhosis and gastrointestinal bleeding [Classics Series]
1. In cirrhotic patients who presented with gastrointestinal bleeding, patients treated with ceftriaxone were significantly less likely to develop proved...
