• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Cohort study suggests that functional impairment and decline are common in middle age

byEvelyn NguyenandDeepti Shroff Karhade
November 15, 2017
in Chronic Disease, Neurology, Psychiatry
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Functional impairment in activities of daily living (ADLs) and/or instrumental ADL (IADL), functional decline, and shifts between independence and functional impairment are all common in middle age.

2. Risk factors for functional impairment include health status, behaviors related to health, and sociodemographics.

Evidence Rating Level: 1 (Excellent)

Study Rundown: Independent living requires the ability to carry out basic ADLs, which includes activities such as dressing or bathing.  Functional impairment, which is difficulty performing ADLs, is often associated with the elderly.  Although such impairment often also occurs in middle age, there is very limited information for this demographic regarding this issue.  This cohort study evaluated the epidemiology and clinical course of functional impairment in middle age.  Researchers used longitudinal data to evaluate adults 50 to 56 years of age who were not functionally impaired at the start of the study.  For up to 20 years of follow-up, participants were assessed for functional impairment (defined as difficulty in performing at least one ADL or IADL) every 2 years.  The authors found that all of the following were common in middle age: functional impairment, functional decline, and shifts back and forth between independence and impairment.  Greater understanding about functional impairment in middle age may assist in developing prevention and management strategies for this demographic.

A strength of the study is the use of a sizable, nationally representative sample of adults from the Health and Retirement Study (HRS).  One limitation is the use of self-reported data for functional status.  In addition, considering that participants were assessed every 2 years, functional impairment may have been underestimated if shorter periods of impairment were not included.

Click to read the study in the Annals of Internal Medicine

RELATED REPORTS

Incidence and prevalence of dementia among US Medicare beneficiaries between 2015 – 2021

No difference between pharmacologic treatments in age-related macular degeneration risk reduction

Patients with varicose veins may be at an increased risk of dementia

Relevant Reading: Middle-aged and mobility-limited: prevalence of disability and symptom attributions in a national survey

In-Depth [prospective cohort]: This study used nationally representative longitudinal data from the HRS, which enrolls new participants every 6 years, to study 6 874 adults who were 50 to 56 years of age at the time of study enrollment (1992, 1998, or 2004).  Every 2 years until 2014, participants were assessed for difficulty in performing any of 5 ADLs or 5 IADLs.  The ADLs studied included bathing, dressing, eating, getting out of a bed or chair, and toileting.  The IADLs studied included making telephone calls, managing medications, managing money, shopping for groceries, and making meals.  By age 64, 22% of participants reported ADL impairment.  Within two years of the first impairment incident, 37% of participants had recovered ADL independence, 50% were either stable or had improved to a level that was below full recovery of independence, 9% had functionally worsened, and 4% were deceased.  Within 10 years of the first impairment, 28% had recovered, 37% were stable or improved, 16% had worsened, and 19% were deceased.  By age 64, 19% of participants reported IADL impairment.  Other findings were similar to that of ADLs.  Risk factors for functional impairment include health status (e.g. chronic medical conditions), behaviors related to health (e.g. low physical activity), and sociodemographics (e.g. low income).

Image: PD

©2017 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: dementia
Previous Post

2 Minute Medicine Rewind November 13, 2017

Next Post

Dabigatran shown to be a safe and effective alternative to warfarin for reducing stroke risk in atrial fibrillation

RelatedReports

Chronic Disease

Incidence and prevalence of dementia among US Medicare beneficiaries between 2015 – 2021

May 31, 2025
Quick Take: Association of Visual Impairment With Economic Development Among Chinese Schoolchildren
Chronic Disease

No difference between pharmacologic treatments in age-related macular degeneration risk reduction

May 8, 2025
Cardiology

Patients with varicose veins may be at an increased risk of dementia

May 5, 2025
Public Health

Caregivers of people with dementia may benefit from online decision aid when managing firearm access

October 22, 2024
Next Post
Lariat device for left atrial appendage exclusion associated with adverse events

Dabigatran shown to be a safe and effective alternative to warfarin for reducing stroke risk in atrial fibrillation

Sleep duration inversely related to childhood type 2 diabetes risk makers

Lifestyle interventions and certain medications reduce risk of diabetes in high risk individuals

Radiation dose associated with increased heart disease in Hodgkin lymphoma survivors

Heart failure readmission prevention program may have inadvertent consequences

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Food compounds associated with disease activity in inflammatory bowel disease 
  • Abbreviated MRI is superior to whole-breast ultrasound for detection of cancer in dense breasts
  • Volumetric diet and time-restricted eating demonstrate similar outcomes for weight reduction
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.