• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Infectious Disease

Comparative outcomes between COVID-19 and influenza patients placed on veno-venous extracorporeal membrane oxygenation

byBrian DoughertyandAlex Chan
April 22, 2021
in Infectious Disease, Pulmonology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

RELATED REPORTS

Vaccination boosted immunity acquired from previous SARS-CoV-2 infection

Single-dose Ad26.COV2.S vaccine provides moderate protection against Covid-19 related outcomes

BNT162b2 safe and efficacious in children 5 to 11 years of age

1. COVID-19 patients with severe ARDS on veno-venous extracorporeal membrane oxygenation were nearly three times as likely to experience in-hospital death compared with influenza patients.

Evidence Level Rating: 3 (Average)

Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is an established supportive therapy for patients with severe acute respiratory distress syndrome (ARDS) refractory to more conventional therapies. As the COVID-19 pandemic continues to place stress on the healthcare system, providers may have to triage the use of V-V ECMO among patients with ARDS secondary to COVID-19 or to influenza, which peaks during winter months and will again impose a dual burden on healthcare workers. There are very little data highlighting the differences between using V-V ECMO to manage ARDS in these two patient populations, and this study evaluated the differences in patient characteristics and clinical outcomes. Using data from a large quaternary medical center, the first 32 adult COVID-19 patients with severe ARDS placed on V-V ECMO were compared with the last 28 adult influenza patients with severe ARDS placed on V-V ECMO. The primary outcome was survival to hospital discharge. Secondary outcomes included ECMO-related complications, such as bleeding events, air emergencies, and organ failure. COVID-19 patients were significantly older (47.8±10.3 vs. 41.2±12.8 years, p = 0.033). Furthermore, there were significantly more Hispanic patients in the COVID-19 group and the prevalence of diabetes was significantly higher. The duration of V-V ECMO was significantly longer in the COVID-19 cohort with a mean of 12.4 days compared with 7.7 days in the influenza cohort (p = 0.002); additionally, the time to canulation from symptom onset and ICU admission was longer. The need for a circuit change due to oxygenation failure was also higher among COVID-19 patients. Finally, crude in-hospital mortality was significantly higher in the COVID-19 cohort compared with the influenza cohort (65.6% vs. 36.3%). Cox regression modeling adjusted for age, race, organ failure while on ECMO, and Charles Comorbidity Index (CCI) revealed an adjusted hazard ratio over sixty days for COVID-19 patients compared to influenza patients of 2.81 (95% CI 1.07 to 7.35). In all, this retrospective analysis revealed that COVID-19 patients with severe ARDS on V-V ECMO had a nearly threefold increased risk of in-hospital death compared with influenza patients. The limitations of this study were myriad, including a single center perspective, but suggest that more robust data are needed to define critical care management of COVID-19 patients with ARDS on V-V ECMO.

Click to read the study in the AJS

Image: PD

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: extracorporeal membrane oxygenation (ECMO)SARS-CoV-2
Previous Post

#VisualAbstract: Dolutegravir-containing antiretroviral regimens show effective viral suppression in pregnant women with HIV-1

Next Post

#VisualAbstract: No differences in survival in patients with esophageal cancer treated with neoadjuvant chemotherapy or chemoradiotherapy followed by esophagectomy

RelatedReports

Decreased expression of nasal ACE2 may be correlated with lower prevalence of COVID-19 in children
Chronic Disease

Vaccination boosted immunity acquired from previous SARS-CoV-2 infection

May 13, 2022
Novel coronavirus identified from patients with pneumonia in Wuhan, China
Chronic Disease

Single-dose Ad26.COV2.S vaccine provides moderate protection against Covid-19 related outcomes

May 13, 2022
Decreased expression of nasal ACE2 may be correlated with lower prevalence of COVID-19 in children
Chronic Disease

BNT162b2 safe and efficacious in children 5 to 11 years of age

May 13, 2022
Masks for personal protection for SARS-CoV-2 infection
Chronic Disease

Adding mask recommendation did not significantly reduce the SARS-CoV-2 infection rate

May 13, 2022
Next Post
#VisualAbstract: Liver metastases and LDH levels may be superior prognostic biomarkers for patients with metastatic melanoma

#VisualAbstract: No differences in survival in patients with esophageal cancer treated with neoadjuvant chemotherapy or chemoradiotherapy followed by esophagectomy

Combined MRI and NIH stroke scores may predict stroke prognosis

Levetiracetam not clinically effective nor cost-effective compared to valproate for newly diagnosed generalized or unclassified epilepsy

Physical therapy reduces pain in adults with knee osteoarthritis

Web-based intervention of self-directed strengthening exercises improved pain and functional capacity for patients with osteoarthritis

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • #VisualAbstract: Pretreatment with radiotherapy and two cycles of concurrent cisplatin may reduce toxicity in locally advanced nasopharyngeal carcinoma
  • High pediatric sequential organ failure assessment (pSOFA) score may predict hospital mortality in emergency department setting
  • #VisualAbstract: Increased physical activity is a long-term protective factor for dementia
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.