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✦EvidencePulse™by 2 Minute Medicine3 reportsYou askedtop stroke trials 2026Synthesizing medical evidence...Top 2026 stroke trial results:OCEANIC — ischemic stroke: 6.2% vs 8.4%OPTION* — mRS 0–1: 43.6% vs 34.2%ORIENTAL* — mRS 0–2: 58.6% vs 46.6%*Higher sICH in intervention armsParticipants randomizedNOCEANIC12,327OPTION570ORIENTAL564Ask about guidelines or landmark trials...↑Try EvidencePulse™Ask the evidence. Get the signal.Try it now →
Home All Specialties Chronic Disease

Evidence suggests that patient navigators and provider reminders may improve follow-up after positive fecal blood test

byCaitlyn HuiandDeepti Shroff
October 11, 2017
in Chronic Disease, Gastroenterology, Oncology, Public Health, Surgery
Reading Time: 2 mins read
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1. Interventions including patient navigators and provider reminders may be associated with improved follow-up for positive fecal blood tests.

2. There is low evidence to support system-level interventions following colonoscopy screening.

Evidence Rating Level: 1 (Excellent)

Study Rundown: Colorectal screening programs are important public health initiatives, as they have been shown to reduce mortality and morbidity from colorectal cancer. These screening programs involve fecal occult blood testing in adults aged 50 to 75 years, annually or biennially. Despite these screening initiatives, colonoscopy follow-up is challenging as it involves the interaction of several levels of care and multiple healthcare providers. The authors of this systematic review aimed to compare the interventions in place to improve rates of follow-up colonoscopy for adults after a positive fecal occult blood test. Generally, the results showed increased evidence for patient navigators and provider reminders after a positive test. This study has several limitations. First, the studies had heterogeneous designs and outcomes measurements; therefore, a meta-analysis could not be performed. Second, there was a high or very high risk of bias in over half of the studies included in the analysis.

Click to read the study in the Annals of Internal Medicine

Relevant Reading: Patient Outreach to Promote Colorectal Cancer Screening Among Patients With an Expired Order for Colonoscopy

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In-Depth [systematic review]: Data was obtained from the Cochrane Central Register of Controlled Trials, PubMed, and Embase from database inception through June 2017. Studies were included that were randomized and nonrandomized, focusing on colonoscopy as a follow-up of positive results on fecal blood tests. Two independent reviewers extracted data and performed a quality assessment. Of the 23 studies included in the review, there was low-evidence for system-level interventions and moderate evidence for patient navigators and provider reminders or performance data. There were proportions for test-positive patients who had follow-up colonoscopy with and without the intervention in 17 of the studies. Absolute differences were -7.4 percentage points (95% CI, -19 to 4.3 percentage points) to 25 percentage points (CI, 14 to 35 percentage points).

Image: CC/Wiki

©2017 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: colonoscopyfecal immunochemical testsFecal Occult
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✦ EvidencePulse™ by 2 Minute Medicine 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... Try EvidencePulse™ Get the signal. Try it now → Physician-trained medical AI by 2 Minute Medicine

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