Tag: colonoscopy

1. In this microsimulation model of U.S. patients aged 50-79, high-intensity surveillance following colorectal adenoma provided clinically significant benefits over low-intensity surveillance at acceptable cost. 2. In nearly all evaluated alternative scenarios, the absolute cost-effectiveness of high-intensity surveillance remained under $100,000 per quality-adjusted life-year (QALY) gained. Compared with low-intensity surveillance,...
1. In this microsimulation model of U.S. patients aged 50-79, high-intensity surveillance following colorectal adenoma provided clinically significant benefits over low-intensity surveillance at acceptable cost. 2. In nearly all evaluated alternative scenarios, the absolute cost-effectiveness of high-intensity surveillance remained under $100,000 per quality-adjusted life-year (QALY) gained. Compared with low-intensity surveillance,...
The most common colorectal cancer (CRC) screening methods are colonoscopy, flexible sigmoidoscopy (FS), and fecal immunochemical testing (FIT). The diagnostic yield of any screening method is dependent on participation, and endoscopic screening consistently shows lower participation rates compared to FIT-based screening. In this analysis of three randomized studies, 30,052...
1. In this randomized controlled trial, cold snare polypectomy with continuous anticoagulation does not increase bleeding risk when compared to hot snare polypectomy with heparin bridging. 2. The cold snare polypectomy procedure had shorter procedure time per lesion and decreased length of hospital stays in comparison to hot snare polypectomy. Evidence...
Pregnancy duration and endometrial cancer risk: nationwide cohort study Full-term pregnancies are strongly associated with a reduced risk of endometrial cancer. Whether this protective association is driven by fecundity, a specific process that occurs during pregnancy, or cumulative number of months pregnancy, however, is unknown. In this cohort study, 2,311,332...
1. In this randomized controlled trial, cold snare polypectomy with continuous anticoagulation does not increase bleeding risk when compared to hot snare polypectomy with heparin bridging. 2. The cold snare polypectomy procedure had shorter procedure time per lesion and decreased length of hospital stays in comparison to hot snare polypectomy. Evidence...
1. Patients with advanced adenomas identified on flex sigmoidoscopy had a significantly increased risk of death from colorectal cancer (CRC) compared to those with no adenomas. 2. There was no difference in cumulative CRC incidence in patients with nonadvanced adenomas as compared to those with no adenomas. Evidence Rating: 1 (Excellent) Study...
1. Sigmoidoscopy was associated with a reduction in the prevalence of colon cancer mortality in men. 2. Sigmoidoscopy did not appear to have a significant protective effect for women with respect to decreasing the rates of colorectal cancer. Evidence Rating Level: 1 (Excellent) Study Rundown: Colorectal cancer (CRC) is one of the...
1. Colonoscopy in veterans was associated with reduced mortality from both left and right-sided colorectal cancer. 2. Mortality was reduced by 61% in patients screened by colonoscopy. Evidence Rating Level: 2 (Good) Study Rundown: Colorectal cancer (CRC) screening serves as a critical element of CRC prevention and management. To date, colonoscopy remains...
1. Interventions including patient navigators and provider reminders may be associated with improved follow-up for positive fecal blood tests. 2. There is low evidence to support system-level interventions following colonoscopy screening. Evidence Rating Level: 1 (Excellent) Study Rundown: Colorectal screening programs are important public health initiatives, as they have been shown to...