• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Psychiatry

Excitatory noninvasive brain stimulation interventions improved negative symptoms in schizophrenia

byDanyaal AnsariandNicholas Ng Fat Hing
September 7, 2022
in Psychiatry, Wellness
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Excitatory Noninvasive Brain Stimulation Intervention (NIBS) protocols over the left dorsolateral prefrontal cortex were associated with significantly large improvements in the severity of negative symptoms.

2. None of the investigated NIBS approaches was associated with significantly different changes in positive symptom severity compared to control groups.

Evidence Rating Level: 2 (Good)

According to the 2019 Global Burden of Disease Study, schizophrenia presents a significant burden worldwide. The negative symptoms of schizophrenia significantly impact patients’ quality of life and unfortunately, respond poorly to antipsychotics. As an alternative, noninvasive brain stimulation (NIBS) therapies may be successful in alleviating these symptoms, but their effectiveness has not yet been studied. As a result, the objective of the present study was to evaluate the efficacy of NIBS interventions in alleviating the negative symptoms of schizophrenia.

Of 4867 identified records, the present study included 48 randomized clinical trials (n=211, 30.6% females) from database inception to December 2021. Studies were included if they included patients with schizophrenia who underwent NIBS interventions. Studies were excluded if they did not investigate negative symptoms and included patients other than schizophrenia/schizoaffective disorder. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were followed. Pair-wise meta-analytic procedures were conducted using a random-effects model. Results demonstrated that NIBS treatments over the left dorsolateral prefrontal cortex were linked to a large reduction in the severity of negative symptoms. Furthermore, none of the investigated NIBS approaches was associated with significantly different changes in positive symptom severity.

Despite these findings, the study was limited by the heterogeneity of participants which may have underpowered the study. However, the present study demonstrated the potential for NIBS to relieve the negative symptoms of schizophrenia.

RELATED REPORTS

Schizophrenia incidence sharply increased following cannabis legalization

Teva: long acting olanzapine TEV’749 or Zyprexa shows success in schizophrenia

Levels Of MMP-2 and TNF-α May Be Associated With The Inflammatory Processes Underlying Schizophrenia

Click to read study in: JAMA Psychiatry

Image: PD

©2022 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: brain stimulationnegative symptomsNIBSpositive symptomsschizoaffectiveschizophrenia
Previous Post

#VisualAbstract: Nirmatrelvir associated with improved COVID-19 outcomes in older adults

Next Post

CT not sufficient to rule out early subarachnoid hemorrhage [Classics Series]

RelatedReports

Parental cannabis use increasing, cigarette use decreasing
Chronic Disease

Schizophrenia incidence sharply increased following cannabis legalization

May 19, 2025
Pharma

Teva: long acting olanzapine TEV’749 or Zyprexa shows success in schizophrenia

January 27, 2025
Combined MRI and NIH stroke scores may predict stroke prognosis
Psychiatry

Levels Of MMP-2 and TNF-α May Be Associated With The Inflammatory Processes Underlying Schizophrenia

April 9, 2024
Shared decision-making tool for antidepressants improves patient and physician satisfaction
Wellness

Wellness Check: Mental Health

April 4, 2024
Next Post
The ABCD2 score: Risk of stroke after Transient Ischemic Attack (TIA) [Classics Series]

CT not sufficient to rule out early subarachnoid hemorrhage [Classics Series]

The ABCD2 score: Risk of stroke after Transient Ischemic Attack (TIA) [Classics Series]

Thrombolysis harmful in acute ischemic strokes with large area of parenchymal hypoattenuation [Classics Series]

Masks for personal protection for SARS-CoV-2 infection

Monkeypox data in Spain suggests close contact as main method of transmission

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Reductions in pain catastrophizing are associated with improvements in emotional functioning
  • Repeated medial branch blocks do not improve pain outcomes for thermal radiofrequency ablation
  • Early screening for emotional and cognitive issues may improve psychiatric outcomes for stroke patients
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.