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EvidencePulse™ by 2 Minute Medicine 2026 evidence scan 3 reports You asked top stroke trials 2026 Synthesizing medical evidence... Top 2026 stroke trial results: OCEANIC — ischemic stroke: 6.2% vs 8.4% OPTION* — mRS 0–1: 43.6% vs 34.2% ORIENTAL* — mRS 0–2: 58.6% vs 46.6% *Higher sICH in intervention arms Participants randomizedN OCEANIC 12,327 OPTION 570 ORIENTAL 564 Ask about guidelines or landmark trials... ↑ Try EvidencePulse™ Ask the evidence.
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Home All Specialties Chronic Disease

Homosexual adolescent males more likely to misuse steroids

byCordelia RossandMarc Succi, MD
March 18, 2014
in Chronic Disease, Endocrinology, Pediatrics
Reading Time: 3 mins read
Testosterone and estrogen exert independent effects in the pathogenesis of male hypogonadism
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Image: PD 

1. Sexual minority (homosexual or bisexual) boys had a significantly greater lifetime prevalence of anabolic-androgenic steroid (AAS) misuse compared to heterosexual boys (21% vs 4%).

2. As compared to heterosexual boys, sexual minority boys also reported significantly greater levels of moderate and severe AAS misuse. 

Evidence Rating Level: 2 (Good)

Study Rundown: Anabolic-androgenic steroids (AAS) are substances often taken to enhance strength, performance, and muscularity. Sexual minority (homosexual and bisexual) adolescent males may be at increased risk of AAS misuse in addition to and as a result of other maladaptive outcomes, such as substance abuse, depression, and body image dissatisfaction. The current study examined the prevalence of lifetime misuse of AAS in relation to sexual orientation in US adolescent boys. Sexual minority boys were found to have a significantly greater lifetime prevalence of AAS misuse compared to heterosexual boys (21% vs 4%). Sexual minority boys also reported significantly greater levels of moderate and severe AAS misuse. Depressive symptoms/suicidality, victimization, and substance use were all significant intermediate variables. One limitation of the study is its cross-sectional design, which prevents identification of temporal influences or bidirectional relationships. These results have implications for prevention efforts addressing AAS misuse in sexual minority adolescent boys, which physicians could address with their patients at routine healthcare visits.

Click to read the study, published today in Pediatrics

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Relevant Reading:  Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence

In-Depth [cross-sectional study]: A total of 17,250 adolescent males were surveyed, with 635 (3.7%) classified as sexual minorities, identifying as either homosexual or bisexual. Data was taken from the Youth Risk Behavior Survey (YRBS). Sexual minority boys were found to have a significantly greater lifetime prevalence of AAS misuse compared to heterosexual boys (21% vs 4%, OR = 5.8, 95% CI 4.1-8.2). As compared to heterosexual boys, sexual minority boys also reported significantly greater levels of moderate (8% vs 1.5%, OR = 5.7, 9% CI 3.4-9.6) and severe (4% vs 0.7%, OR = 5.7, 95% CI 2.7-11.9) AAS misuse. Simultaneous multiple mediation indicated that sexual minority classification was significantly associated with increased victimization, increased depressive symptoms/suicidality, and increased substance use; these three variables were all associated with increased AAS misuse. With these variables controlled, the direct effect of sexual minority status on AAS misuse decreased, but remained significant. Substance use appeared to have a stronger association with AAS misuse than depressive/suicidality and victimization.

More from this author: Firearm-related hospitalizations in children represent a heavy burden; Intentional injuries leading to ED visits often occur at school; Sexting linked to other sexual behaviors among teens; Revised autism screening tool (M-CHAT-R/F) may allow for earlier diagnosis; AAP policy supports consumption of only pasteurized dairy products

©2012-2014 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT.

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