• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Pediatrics

Hyoscine butylbromide and acetaminophen have comparable effects for pediatric non-specific colicky abdominal pain

byDavy LauandAlex Chan
December 9, 2020
in Pediatrics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Hyoscine butylbromide and acetaminophen have comparable and significant analgesic effects for pediatric non-specific colicky abdominal pain.

Evidence Rating Level: 1 (Excellent)

Cases of pediatric abdominal pain are a daily occurrence in hospital emergency wards. However, current analgesic recommendations for pediatric abdominal pain are not being adhered to, with two-thirds of patients not receiving any analgesia, and approximately half still experiencing pain post-discharge. A potential factor for this is the lack of analgesic guidelines for non-specific abdominal pain, which comprises two-thirds of abdominal pain cases. Acetaminophen is widely used to treat a variety of painful conditions, but there is insufficient data to demonstrate its effectiveness for abdominal pain, Hyoscine butylbromide (HBB) is an oral antispasmodic medication that has some studies supporting its effectiveness. The current study was a randomized controlled trial to determine whether HBB had superior pain-relieving abilities compared to acetaminophen, for pediatric non-specific colicky abdominal pain. The study population consisted of 236 children ages 8-17 (mean±SD age was 12.4±3), with 120 patients given 10 mg of HBB and 116 given 15 mg/kg of acetaminophen. Each patient presented to a hospital in London, Ontario with a self-reported pain score of at least 40 mm on a 100 mm visual analogue scale (mean pain score was 60±18 mm for HBB, and 62±17 mm for acetaminophen). The primary outcome was pain score 80 minutes after administering the analgesic, to reflect the drugs’ peak action. Overall, the results showed no difference in pain score: For HBB, the mean score was 29±26 mm, while for acetaminophen, it was 30±29 mm. The adjusted difference between the groups was 1 mm (95% CI -7 to 7 mm). Furthermore, no significant differences were found for requirement of emergency analgesia, nor for adverse events and complications. In conclusion, HBB is not superior to acetaminophen for non-specific colicky pediatric abdominal pain, although both forms of analgesia can produce a clinically significant reduction in pain.

Click to read the study in CMAJ

Image: PD

©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

RELATED REPORTS

Trimethoprim-sulfamethoxazole during pregnancy does not reduce risk of prematurity

2 Minute Medicine Rewind May 19th, 2025

Casting only may be non-inferior to surgery for management of medial epicondyle fractures

Tags: pain controlpediatrics
Previous Post

#VisualAbstract: Rilonacept may lower pericarditis recurrence in patients with relapsing pericarditis

Next Post

Improved contraception use with progestogen-only pill and rapid access vs emergency contraception

RelatedReports

Implementation of pneumococcal vaccine programs linked to decreased antibiotic prescription
Infectious Disease

Trimethoprim-sulfamethoxazole during pregnancy does not reduce risk of prematurity

June 9, 2025
Weekly Rewinds

2 Minute Medicine Rewind May 19th, 2025

May 19, 2025
Orthopedic Surgery

Casting only may be non-inferior to surgery for management of medial epicondyle fractures

May 17, 2025
Biosimilar to infliximab shows equivalent safety and efficacy for treating Crohn’s disease
Weekly Rewinds

2 Minute Medicine Rewind May 12, 2025

May 14, 2025
Next Post
1 in 5 US women report delayed contraceptive initiation after sexual debut

Improved contraception use with progestogen-only pill and rapid access vs emergency contraception

#VisualAbstract: Addition of indoximod to taxane chemotherapy does not improve survival in patients with metastatic breast cancer

#VisualAbstract: Addition of indoximod to taxane chemotherapy does not improve survival in patients with metastatic breast cancer

Sotagliflozin reduces hospitalizations and urgent visits for patients with diabetes and worsening heart failure

#VisualAbstract: Acamprosate found an effective and tolerable interventions for alcohol dependence

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Dapagliflozin may improve outcomes in patients with metabolic dysfunction-associated steatohepatitis
  • Early induction of labour reduces shoulder dystocia rates in large for gestational age fetuses
  • Sacituzumab tirumotecan may have a role in the treatment of metastatic non-small cell lung cancer
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.