ICD-10-CM code · FY2027
E21.1 Secondary hyperparathyroidism, not elsewhere classified
BillableValid for claims as a specific diagnosis code
About E21.1
- Code
- E21.1
- Billable
- Yes
- Short description
- Secondary hyperparathyroidism, not elsewhere classified
- Category
- E21 Hyperparathyroidism and other disorders of parathyroid gland
- Block
- E20-E35 Disorders of other endocrine glands
- Chapter
- 4 Endocrine, nutritional and metabolic diseases
- Code set
- FY2027, October 1, 2026 to September 30, 2027
EvidencePulse™by 2 Minute Medicine®
Go deeper into hyperparathyroidism.
Ask about the latest evidence, the landmark trials or what guidelines recommend, with every study cited. No ads, no sponsored answers.
Coding notes for E21.1
Excludes1 Not coded here: never report these together with this code (use the code given instead).
- secondary hyperparathyroidism of renal origin (N25.81)
Also applies, from E21 Hyperparathyroidism and other disorders of parathyroid gland
Excludes1 Not coded here: never report these together with this code (use the code given instead).
Excludes2 Not part of this condition, but a patient can have both: report both codes when both apply.
- familial hypocalciuric hypercalcemia (E83.52)
Block E20-E35 notes (apply to every code in it)
Chapter 4 notes (apply to every code in it)
Note
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Related codes in E21
Latest research on hyperparathyroidism
- Upacicalcet reduced parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism in PATH-1 and PATH-2
- Parathyroidectomy does not impact renal function in adults with primary hyperparathyroidism
- Primary hyperparathyroidism associated with an increased risk of fractures and cardiovascular events
- Parathyroidectomy associated with a reduction in fracture risk among adults with primary hyperparathyroidism
- #VisualAbstract: Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis
2MM+
Read the research behind every diagnosis
2MM+ gives you every study summary in full, Classics downloads of the landmark trials, EvidencePulse and HypeCheck, and ad-free reading.
See 2MM+ plansICD-10-CM FY2027 code set, as published by the CDC National Center for Health Statistics (NCHS) and CMS, effective October 1, 2026 to September 30, 2027. Codes, titles and notes are shown as published. Check payer rules and the official guidelines before billing. This page is not medical advice.
Get the app