• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Oncology

Isolated mild/moderate thrombocytopenia may not require intervention

byShyam AkulaandCordelia Ross
June 11, 2018
in Oncology, Pediatrics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. In a review of children who presented to a specialist hematology clinic with isolated mild or moderate low platelet counts, though causes were variable, most required no interventions.

2. Pediatric patients with isolated mild or moderate thrombocytopenia may not need specialist referral to hematology in most circumstances.

Evidence Rating Level: 2 (Good)

Study Rundown: In pediatric patients, low platelet counts are a frequent finding, with underlying causes ranging from completely benign to serious conditions, such as leukemia. Thus, low platelet count is a frequent cause for referral to a specialist pediatric hematologist. In this study, the authors reviewed a cohort of 113 patients referred to hematology for isolated mild or moderate low platelet counts; findings showed that 11% required intervention of any kind, and only 3% required hematology intervention. The causes of the low platelet counts in this cohort were varied, but most patients had low platelets due to either no known cause or to an immune thrombocytopenia. Most patients in the cohort later had normal platelet counts, suggesting that in many cases, the isolated mild or moderate low platelets self-resolve. Using these results, the authors suggested that general practitioners need not refer their patients to specialist hematologists for every case of isolated mild or moderate low platelets, and that reserving referrals would both improve efficiency of the health system and reduce unnecessary anxiety for patients and their families. This study was limited by its relatively small sample from a single institution, though these results provide a first set of data to assist providers in considering referrals, and repeat blood work.

Click to read the study, published today in Pediatrics

Relevant Reading: Clinical practice: immune thrombocytopenia in pediatrics

In-Depth [retrospective cohort]: Participants were recruited at the University of Alabama at Birmingham (UAB) Pediatric Hematology-Oncology outpatient clinic from all patients with an ambulatory referral for isolated thrombocytopenia on complete blood count. Mild thrombocytopenia was defined as a platelet count between 101-140,000/ul, moderate between 51-100,000/ul, and severe as <50,000/ul. Of the 113 patients referred for evaluation of isolated thrombocytopenia, 48 presented with mild thrombocytopenia and 65 presented with moderate thrombocytopenia. 15 patients of the 113 required intervention, though most (12) from non-hematology specialties, particularly rheumatology or gastroenterology. Of the patients reviewed, none had severe thrombocytopenia after observation (87%) or intervention (13%) at the time the study concluded its analysis in January 2018, with periods of review ranging from 1 to 5 years for each child.

RELATED REPORTS

High emergency department pediatric readiness associated with decreased mortality

Intimate partner violence associated with poor socioemotional development in children

Vaccines for Zaire Ebola virus disease are safe and generate an immune response

Image: PD

©2018 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: hematologypediatricsthrombocytopenia
Previous Post

Recombinant human pentraxin 2 slows the decline in lung function for patients with idiopathic pulmonary fibrosis

Next Post

2 Minute Medicine Rewind June 11, 2018

RelatedReports

Quick Take: Impact of scribes on emergency medicine doctors’ productivity and patient throughput: multicentre randomised trial
Emergency

High emergency department pediatric readiness associated with decreased mortality

January 16, 2023
Meeting families, demographic information affect child abuse work-up
Pediatrics

Intimate partner violence associated with poor socioemotional development in children

January 5, 2023
2 Minute Medicine Rewind November 23 – November 30, 2014
Emergency

Vaccines for Zaire Ebola virus disease are safe and generate an immune response

January 4, 2023
Fewer work hours linked to greater likelihood of continued breastfeeding
Gastroenterology

Formula diets not associated with greater gastrointestinal intolerance than breast feeding

December 29, 2022
Next Post
Postextubation administration of high-flow oxygen leads to reduced reintubation and respiratory failure

2 Minute Medicine Rewind June 11, 2018

Treatment of subclinical hypothyroidism ineffective in older adults

Increased attending supervision may not reduce medical errors and may decrease educational outcomes

African American and Hispanic youth more likely to discontinue ADHD treatment

Exercise linked to reduced mortality in survivors of childhood cancer

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Catheter ablation reduces rates of persistent atrial fibrillation and atrial tachyarrhythmia
  • Deep intronic FGF14 repeat expansion associated with late-onset cerebella ataxia
  • Plant-based diets may be associated with lower risk of aggressive prostate cancer
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options