• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Dermatology

Pregnancy outcomes in women with moderate-to-severe psoriasis

byDavy LauandAlex Chan
February 10, 2021
in Dermatology, Obstetrics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

RELATED REPORTS

#VisualAbstract: Ruxolitinib use may be associated with higher incidences of nonmelanoma skin cancers

#VisualAbstract: Solid organ transplant recipients are at an increased risk of developing non-melanoma skin cancers

Presence of second midwife during the second active stage of labour reduces the risk of severe perineal trauma

1. Pregnant women using biologic treatments for psoriasis, both before and during pregnancy, were found to have similar pregnancy outcomes as the general American population.

Evidence Rating Level: 2 (Good)

Psoriasis is a chronic inflammatory skin disease affecting 7 million adults in the United States. It has been hypothesized that the chronic inflammatory state and association with psoriasis-related comorbid conditions such as diabetes and cardiovascular predispose pregnant women to complications. However, there is limited data due to exclusion of pregnant patients from clinical trials, and because psoriasis patients often stop treatment during pregnancy. The current prospective cohort study analyzed the fertility rate and pregnancy outcomes from patients in a longitudinal registry who were eligible for systemic and biologic therapies for their psoriasis. Out of 2,224 women of childbearing age (18-45 years) in the registry, there were 298 pregnancies from 220 patients between 2007 and 2019 (12,929 patient years). The fertility rate was 18.9 per 1000 women, which was lower than the general US population (59.1 per 1000 women). Out of the 298 pregnancies, there were 244 births including 1 stillborn (81.9%), 41 spontaneous abortions (13.8%), and 13 terminations (4.4%). 90.9% of live-births were full-term and 9.1% were premature. 94.7% of newborns were considered healthy, 10 infants (4.1%) had a neonatal issue, and 2 (0.8%) had congenital anomalies. As well, 252 of these pregnancies were in women exposed to biologic therapy both before or during pregnancy. The remaining 46 pregnant women may have received a non-biologic therapy, such as phototherapy, before or during pregnancy. The infants with congenital anomalies were from women who received the biologic ustekinumab, 1 outside of the prenatal period and 1 during. Overall, the pregnancy outcomes in terms of live-born infants, spontaneous abortions, terminations, and congenital abnormalities, are not significantly different from between the general US population and women using biologic treatments for psoriasis, although further studies using pregnancy-specific registries may be needed to increase the sample size.

Click to read the study in JAMA Dermatology

Image: PD

©2021 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: dermatologyobstetrics
Previous Post

#VisualAbstract: Adavosertib plus gemcitabine improves survival in platinum-resistant recurrent ovarian cancer

Next Post

#VisualAbstract: Endocrine therapy plus oral S-1 improves invasive disease-free survival in patients with ER⁺ breast cancer

RelatedReports

#VisualAbstract: Ruxolitinib use may be associated with higher incidences of nonmelanoma skin cancers
StudyGraphics

#VisualAbstract: Ruxolitinib use may be associated with higher incidences of nonmelanoma skin cancers

April 26, 2022
#VisualAbstract: Solid organ transplant recipients are at an increased risk of developing non-melanoma skin cancers
StudyGraphics

#VisualAbstract: Solid organ transplant recipients are at an increased risk of developing non-melanoma skin cancers

April 12, 2022
Women electing abortion more likely to be victims of domestic violence
Chronic Disease

Presence of second midwife during the second active stage of labour reduces the risk of severe perineal trauma

April 7, 2022
Poverty, preterm birth demonstrate additive effect on cognition
Chronic Disease

2 Minute Medicine Rewind March 28th, 2022

March 28, 2022
Next Post
#VisualAbstract: Endocrine therapy plus oral S-1 improves invasive  disease-free survival in patients with ER⁺ breast cancer

#VisualAbstract: Endocrine therapy plus oral S-1 improves invasive disease-free survival in patients with ER⁺ breast cancer

Risk factors for SARS-CoV-2 seropositivity in health care workers

Video-based behavioral intervention benefits clinical skin examinations

Tirbanibulin ointment potentially effective for actinic keratosis treatment

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Long-acting cabotegravir significantly decreases incidence of HIV compared to daily oral tenofovir
  • Oral methylprednisolone may reduce risk of progressive renal failure in patients with IgA nephropathy: TESTING Trial
  • #VisualAbstract: Adjuvant capecitabine improves long-term survival in early breast cancer
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.