• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Stepped-care management useful for chronic pain treatment in veterans (ESCAPE Trial)

byShayna BejaimalandJames Jiang
March 12, 2015
in Chronic Disease
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Stepped-care intervention (analgesia with self-management strategies followed by cognitive behavioral therapy) was associated with decreased pain-related disability, interference, and severity in veterans with chronic pain.

Evidence Rating Level: 1 (Excellent)

Study Rundown: With the high prevalence of chronic pain syndromes in American veterans, it has become increasingly important to determine an effective means of management. Both analgesia and cognitive behavioural therapy (CBT) have been shown to be effective in different pain syndromes previously. However, no studies have examined a stepped-treatment intervention in the veteran population. This randomized controlled trial examined whether a 2-step intervention, consisting of 12 weeks of analgesic therapy coupled with self-management strategies followed by 12-weeks of CBT, was more effective than usual care in decreasing pain-related disability, interference and severity.

This study found that veterans randomized to the stepped-care intervention resulted in statistically significant reductions in pain-related disability, pain interference and pain severity as compared to patients in usual care. Strengths of the study include using validated pain scales for outcome measurement as well as use of intention-to-treat analysis. However, limitations include being a single-blinded, single-centred study with a large number of patient exclusions prior to randomization.

Click to read the study, published today in JAMA Internal Medicine

Relevant Reading: Depression and Pain Comorbidity: A Literature Review

RELATED REPORTS

Reductions in pain catastrophizing are associated with improvements in emotional functioning

The Scan by 2 Minute Medicine®: Billy Joel’s Brain Condition, Gigi Robinson’s Surgical Advocacy, Climate and Cancer Risk, and West Nile Virus Reaches the United Kingdom

Bedside parameters may help predict chronic post-traumatic head and neck pain

In-Depth [randomized controlled trial]: This randomized controlled trial recruited participants from post-deployment and general medicine clinics in a VA Medical Centre from December 2007 to June 2011. Participants were included if they were veterans from the Afghanistan and Iraq conflicts and had self-reported chronic pain for more than 3 months that was moderately disabling. They were randomized in groups of 8 to either stepped-care or usual care. Stepped-care included 12 weeks of analgesic treatment with optimization according to an algorithm coupled with self-management strategies, followed by 12 weeks of CBT. Participants in the usual care arm received education and ‘usual’ pharmacological and non-pharmacological treatment from their physicians. Data on pain-disability, interference and severity were collected at 3, 6 and 9 months post-randomization using three validated assessment scales. Data was analyzed using an intention-to-treat protocol.

Of the 659 patients assessed for this study, 121 were randomized to the stepped-care intervention and 120 were randomized to usual care. At 9 months, there was a decrease in pain-related disability (between-group difference, -1.9, 95%CI -3.2 to -0.7 points, P=0.002), pain interference (between-group difference, -0.8, 95%CI -1.3 to -0.3 points, P=0.003), and pain severity (between-group difference, -6.6, 95%CI -10.5 to -2.7 points, P=0.001) in the stepped-care intervention group as compared to those undergoing usual care.

Image: PD

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: chronic painpain management
Previous Post

Decision aids maybe be underutilized in treating prostate cancer

Next Post

Appropriate use criteria for angiography may frequently miss obstructive coronary artery disease

RelatedReports

Parental nonmedical prescription opioid use linked to adolescent use
Chronic Disease

Reductions in pain catastrophizing are associated with improvements in emotional functioning

June 22, 2025
The Scan by 2 Minute Medicine®:  Ultra-Trail du Mont-Blanc, Taylor Swift, NBA rookie Chet Holmgren and Magic Mushrooms!
The Scan by 2 Minute Medicine®

The Scan by 2 Minute Medicine®: Billy Joel’s Brain Condition, Gigi Robinson’s Surgical Advocacy, Climate and Cancer Risk, and West Nile Virus Reaches the United Kingdom

May 27, 2025
Chronic Disease

Bedside parameters may help predict chronic post-traumatic head and neck pain

May 25, 2025
Parental nonmedical prescription opioid use linked to adolescent use
Chronic Disease

Music listening may be an effective adjunct for pain control

March 25, 2025
Next Post
Appropriate use criteria for angiography may frequently miss obstructive coronary artery disease

Appropriate use criteria for angiography may frequently miss obstructive coronary artery disease

Weekly dalbavancin noninferior to daily therapy for acute skin infection [DISCOVER 1 and 2 Trials]

Novel vaccine cocktail treats Staphylococcus aureus infections in mice (PreClinical)

New genetic link in pulmonary arterial hypertension holds therapeutic promise

Restrictive transfusion threshold non-superior to liberal threshold for post-cardiac surgery patients

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Time-restricted eating does not confer changes in sleep, mood, or quality of life
  • Commonly cited medication triggers may not increase risk of microscopic colitis among older adults
  • Ablation may reduce stroke risk, death, heart failure hospitalization in patients with atrial fibrillation
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.