Tag: adjuvant therapy

1. In a retrospective cohort of 1107 patients with lymph node invasion following primary prostate cancer treatment, the use of adjuvant radiotherapy was associated with a significant improvement in cancer-specific mortality. 2. Two sub-group of patients: 1) Patients with positive lymph node counts of <2, Gleason score 7-10, pT3b/pT4 stage...
Image: PD 1. Delays in initiation of adjuvant chemotherapy following definitive breast cancer surgery are associated with worse outcomes in advanced stage disease and worse survival in hormone receptor positive and HER2 positive cancers. Evidence rating level: 2 (Good) Study Rundown: Previous clinical trials regarding the use of adjuvant chemotherapy following definitive...
Image: PD  Oxaliplatin 1. The 12-gene Recurrence Score can predict recurrence risk and disease-free survival in both stage II and III colon cancer. 2. Higher scores may help predict absolute benefit of oxaliplatin for stage II and IIIA/B disease. Evidence rating level:  2 (Good) Study Rundown: Given the complex treatment options available for...
Image: PD 1. Adjuvant radiotherapy (RT) following local excision reduces the risk for local recurrence (LR) of ductal carcinoma in situ (DCIS) by half at 15 years follow-up. 2. The long-term prognosis of DCIS is favorable and independent of given treatment. Evidence Rating Level: 1 (Excellent) Study Rundown: Preventive cancer screenings have significantly...
Image: PD 1. Pathohistological subtype of pancreatic intraductal papillary mucinous neoplasm (IPMN) was a strong independent predictor for malignancy.  2. Pancreatobiliary type IPMN was associated with poor prognosis as well as malignant behavior and high recurrence potential. Survival rates were similar to pancreatic ductal adenocarcinoma, a cancer with similar tumor biology,...