Tag: anti-arrhythmic

1. Cluster analysis of a population of patients with atrial fibrillation (AF) identified four unique phenotypes using variables not traditionally associated with AF classification. 2. The four phenotypic AF groups were associated with differences in treatment strategies and clinical outcomes. Evidence Rating Level: 3 (Average)     Study Rundown: Atrial fibrillation is the most...

1. In patients with congestive heart failure (CHF) and reduced ejection fraction, mortality was significantly lower in patients who received an implantable cardioverter-defibrillator (ICD) compared those who did not receive one. 2. In these patients, amiodarone did not confer a favorable survival benefit as compared to placebo. Original Date of Publication:...

1. Catheter ablation was found to be more effective than escalated antiarrhythmic drug (AAD) therapy at treating patients with ischemic cardiomyopathy and an implantable cardioverter-defibrillator (ICD) who had ventricular tachycardia (VT) despite AAD therapy. 2. The increased effectiveness was only observed in patients treated with amiodarone at baseline. Evidence Rating Level:...

Image: PD 1. The use of class IC anti-arrhythmic agents flecainide and encainide in patients following myocardial infarction with left ventricular dysfunction increases the risk of death due to arrhythmia and shock. Study Rundown: Venticular arrhythmia is a major cause of cardiac death following myocardial infarction. Thus, the CAST study sought to determine...