Tag: anticoagulation

1. Rates of detected atrial fibrillation (A fib) were significantly higher in postoperative cardiac surgery patients who wore a patch-based heart monitor for 30 days following randomization compared to those who underwent usual care. 2. A significant amount of time spent in A fib (6 hours cumulative, 24 hours cumulative)...
1. Non-vitamin K antagonist oral anticoagulants (NOACs) were associated with decreased stroke/ systemic embolism risk compared to warfarin among patients with nonvalvular atrial fibrillation at high risk for bleeding. 2. In comparison to warfarin, apixaban and dabigatran were associated with reduced risk of major bleeding; however, rivaroxaban was associated with...
1. Therapeutic anticoagulation with rivaroxaban or enoxaparin did not improve clinical outcomes and increased bleeding compared with prophylactic anticoagulation. 2. Net clinical benefit composite of death, thrombotic events, and major or clinically relevant non-major bleeding was not significantly different between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: COVID-19 is associated with...
1. Patients continuing perioperative anticoagulation when undergoing robot-assisted radical prostatectomy did not experience an increased incidence of high-grade bleeding. Evidence Level Rating: 2 (Good) Robot-assisted radical prostatectomy (RARP) is the standard of care for surgical management of localized prostate cancer. As RARP is classified as a hemorrhagic procedure, patients on anticoagulation...
1. Gastrointestinal, genitourinary, or bronchopulmonary bleeding in anticoagulated patients with atrial fibrillation have been associated with higher rates of respective cancer diagnoses. Evidence Rating Level: 2 (Good) Recent registry data suggests that diagnoses of atrial fibrillation (AF) have been associated with higher incidence rates of cancer. Bleeding episodes in anticoagulated patients...
1. Gastrointestinal, genitourinary, or bronchopulmonary bleeding in anticoagulated patients with atrial fibrillation have been associated with higher rates of respective cancer diagnoses. Evidence Rating Level: 2 (Good) Recent registry data suggests that diagnoses of atrial fibrillation (AF) have been associated with higher incidence rates of cancer. Bleeding episodes in anticoagulated patients...
1. Microbleeds increase risk of intracerebral hemorrhage, ischemic stroke, recurrent stroke, and mortality. 2. Microbleeds do not appear to influence the effects of rivaroxaban treatment. Evidence Rating Level: 2 (Good) Cerebral microbleeds are known to be associated with intracerebral hemorrhage and recurrent. Questions have been raised related to antithrombitic treatment for those...
1. Among trauma patients aged 10 to 17, the use of low molecular weight heparin as compared with unfractionated heparin was associated with fewer episodes of venous thromboembolism as well as a reduction in mortality. Evidence Level Rating: 2 (Good) Low molecular weight heparin (LMWH) and unfractionated heparin (UFH) are the...
1. Co-prescription of clarithromycin and direct oral anticoagulants was associated with a higher rate of 30-day hospitalization with hemorrhage when compared with co-prescription of azithromycin. Evidence Rating Level: 2 (Good) In recent years, direct oral anticoagulants (DOACs) like apixaban and rivaroxaban have overtaken vitamin K antagonists as the anti-coagulation drugs of...