Apixaban (eliquis) outperforms Rivaroxaban (xarelto) in venous thromboembolism bleeding risk
1. In the randomized COBRRA trial, apixaban was associated with substantially less clinically relevant bleeding than rivaroxaban in patients with ...
Tag: anticoagulation
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2 Minute Medicine: Pharma Roundup – Pfizer’s Talzenna delays prostate cancer progression, apixaban lowers VTE bleeding risk, Lilly’s retatrutide hits Phase III metabolic targets, and FDA warns Novo Nordisk over safety reporting violations [March 2026]
Pfizer’s Talzenna combo significantly delays progression in frontline prostate cancer Topline results from the Phase 3 TALAPRO-3 study indicate that ...
Early anticoagulation after stroke decreases recurrence without increasing bleeding in patients with atrial fibrillation
1. Recurrent ischemic stroke rates were significantly reduced in patients who started DOAC within 4 days of an acute ischemic ...
#VisualAbstract: Reduced-Dose was Not Non-Inferior to Full-Dose Direct Oral Anticoagulants in Venous Thromboembolism Patients
Click here to read this study in the Lancet. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be ...
Endovascular therapy improves outcomes in vertebrobasilar stroke despite increased risk of bleeding
1. Patients in the endovascular therapy group achieved greater functional outcomes at 90 days. 2. Endovascular therapy resulted in significantly ...
#VisualAbstract: Early Timing of Anticoagulation after Acute Ischemic Stroke with Atrial Fibrillation was Noninferior to Delayed Timing
Click here to read this study in the Lancet. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be ...
Characterizing risk of stroke following anticoagulation reversal in patients with prior intracranial hemorrhage and heart valves
1. In a cohort of patients with mechanical heart valves and a prior history of intracranial hemorrhage (ICH), the risk ...
Novel prophylactic anticoagulation scoring tool helps stratify patients following lower limb trauma
1. The 3-month symptomatic venous thromboembolism rate was 0.7% in patients with TRiP(cast) score < 7 and not receiving anticoagulation. ...
Concomitant selective serotonin reuptake inhibitors and oral anticoagulants may increase risk of bleeding
1. This case-control study found that in patients with atrial fibrillation concomitant Serotonin Reuptake Inhibitor (SSRI) and Oral Anticoagulants (OAC) ...
Use of direct oral anticoagulants should not delay surgical intervention for patients with hip fractures
1. In geriatric patients with hip fractures on direct oral anticoagulants (DOACs), surgical treatment within 48 hours of their last ...
