Tag: antiretroviral therapy

1. Deferral of antiretroviral therapy was associated with a small increase risk in acquired immunodeficiency syndrome (AIDS)-defining cancers at 10-year follow-up in young, human immunodeficiency virus (HIV)-positive patients. 2. The study was inconclusive on the long-term risk association of early antiretroviral therapy initiation and non-AIDS-defining cancers in the patient population....
1. Dolutegravir-based antiretroviral therapy regimens effectively suppressed maternal viral load during pregnancy, supporting their use to prevent vertical transmission. 2. Dolutegravir, emtricitabine, and tenofovir alafenamide fumarate carried relatively low risk of adverse fetal outcomes. Evidence Rating Level: 1 (Excellent) Study Rundown: Initiation of antiretroviral therapy (ART) for pregnant women infected with HIV-1 is important for...
1. Dolutegravir-based antiretroviral therapy regimens effectively suppressed maternal viral load during pregnancy, supporting their use to prevent vertical transmission. 2. Dolutegravir, emtricitabine, and tenofovir alafenamide fumarate carried relatively low risk of adverse fetal outcomes. Evidence Rating Level: 1 (Excellent) Study Rundown: Initiation of antiretroviral therapy (ART) for pregnant women infected with HIV-1...
1. At week 48, there was a similar proportion of participants with plasma HIV-1 RNA ≥ 50 copies per mL between the 8-week and 4-week dosing groups. 2. The safety profile was similar between both dosing groups with no treatment-related deaths. Evidence Rating Level: 1 (Excellent) Study Rundown: Current medications for HIV...
Early evidence has suggested a strong association between HIV viral load and the risk of transmission to an HIV-negative partner, as well as a significant reduction in transmission rates with early initiation of antiretroviral therapy and viral suppression among HIV-positive partners. Previous studies have largely examined HIV transmission rates...
Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study Early evidence has suggested a strong association between HIV viral load and the risk of transmission to an HIV-negative partner, as well...