Tag: aortic stenosis

1. The Portico aortic valve had non-inferior rates of all-cause mortality and disabling stroke at 1 year after randomization compared to commercially available valves. 2. The Portico aortic valve had a higher rate of all-cause mortality and serious adverse events than commercially available valves 30 days after randomization. Evidence Rating Level:...
1. After successful transcatheter aortic valve replacement, compared to an anti-platelet based strategy, patients that received an anti-coagulation strategy including rivaroxaban at a dose of 10 mg daily had a higher risk of death, thromboembolic complications, and bleeding. Evidence Rating: 1 (Excellent) Transcatheter aortic-valve replacement (TAVR) is a treatment option for patients...
1. Patients with asymptomatic severe aortic stenosis receiving early valve replacement had a lower incidence of operative mortality or death due to cardiovascular causes compared to patients receiving conservative care Evidence Level: 1 (Excellent) Aortic stenosis is the most common valvular disease with surgical indications in developed countries, with aortic-valve replacement being...
The association of depression with subsequent dementia diagnosis: A Swedish nationwide cohort study from 1964 to 2016 1. There is a significantly increased risk of dementia in patients with previously diagnosed depression, with the highest risk observed in patients diagnosed with severe depression Evidence Level: 2 (Good) The prevalence of dementia is on...
In patients who have previously undergone coronary artery bypass graft surgery (CABG), surgical aortic valve replacement (SAVR) can be a complicated procedure due to the risks of sternal re-entry and cardiac or graft injury. Transcatheter aortic valve replacement (TAVR) offers a less invasive approach that may be more optimal...
1. In this retrospective cohort study, the rate of 30-day post-procedure stroke after transcatheter aortic valve replacement (TAVR) remained stable during the first five years of US clinical practice. 2. 30-day stroke rates were similar between patients who received dual antiplatelet therapy, oral anticoagulants, or neither at hospital discharge. Evidence Rating...
1. This randomized control trial compared post-surgical outcomes between transcatheter aortic-valve replacement (TAVR) with balloon-expandable valves or surgical valve replacement in low- risk surgical patients, finding that patients randomized to receive TAVR had significantly lower rates of composite death, stroke or rehospitalization after one year. 2. Patients randomized to the...
1. This randomized control trial compared post-surgical outcomes between transcatheter aortic-valve replacement (TAVR) with balloon-expandable valves or surgical valve replacement in low- risk surgical patients, finding that patients randomized to receive TAVR had significantly lower rates of composite death, stroke or rehospitalization after one year. 2. Patients randomized to the...
1. This randomized clinical trial showed that cerebral embolic protection devices did not significantly reduce the risk of CNS infarction among patients with calcific aortic stenosis undergoing SAVR. 2. However, fewer patients experienced delirium at postoperative day 7 in the cerebral embolic protection devices group compared to control. Evidence Rating Level:...
1. When compared with bioprosthetic aortic valve replacements (AVR), mechanical AVRs were associated with increased mortality on the date of surgery and in early days after the operation amongst older Americans. 2. This difference in mortality was not present between the two forms of AVR 30 days after the...