Apixaban (eliquis) outperforms Rivaroxaban (xarelto) in venous thromboembolism bleeding risk
1. In the randomized COBRRA trial, apixaban was associated with substantially less clinically relevant bleeding than rivaroxaban in patients with ...
Tag: bleeding risk
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Clopidogrel monotherapy is superior to aspirin for secondary prevention in coronary artery disease
1. Major adverse cardiovascular and cerebrovascular events were significantly reduced with clopidogrel compared to aspirin alone. 2. There was no ...
Direct oral anticoagulants have similar bleeding risk compared with aspirin
1. In this systematic review and meta-analysis, the non-vitamin K oral anticoagulants apixaban and dabigatran both had similar rates of ...
Active mechanical circulatory support does not reduce mortality in acute myocardial infarction-related cardiogenic shock
1. Early use of mechanical circulatory support did not reduce 6-month all-cause mortality. 2. MCS was associated with increased major ...
Bivalirudin during and post-percutaneous coronary intervention reduces bleeding and mortality compared to heparin monotherapy
1. Bivalirudin during percutaneous coronary intervention plus high-dose infusion after demonstrated decreased all-cause mortality compared to heparin monotherapy. 2. Risk ...
Left atrial appendage occlusion is an effective alternative to oral anticoagulation in atrial fibrillation
1. The overall benefit of left atrial appendage occlusion (LAOO) for prevention of stroke in patients with atrial fibrillation (AF) ...
Abbreviated dual antiplatelet therapy could improve outcome after percutaneous coronary intervention
1. Abbreviated antiplatelet therapy was shown to be noninferior to the standard duration of therapy in net adverse clinical and ...
Clopidogrel monotherapy is superior to aspirin monotherapy for chronic maintenance after percutaneous coronary intervention
1. Clopidogrel monotherapy reduced long-term rates of all-cause mortality, non-fatal myocardial infarction, and stroke after drug-eluting stent placement compared with ...
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Therapeutic anticoagulation increases bleeding risk without improvements in clinical outcomes in patients admitted for COVID-19 and elevated D-dimer
1. Therapeutic anticoagulation with rivaroxaban or enoxaparin did not improve clinical outcomes and increased bleeding compared with prophylactic anticoagulation. 2. ...
