Tag: bleeding risk

1. Clopidogrel monotherapy reduced long-term rates of all-cause mortality, non-fatal myocardial infarction, and stroke after drug-eluting stent placement compared with aspirin monotherapy. 2. The superiority of clopidogrel was seen for both thrombotic and bleeding endpoints and was consistent across demographic groups. Evidence Rating Level: 1 (Excellent)  Study Rundown: Patients who receive percutaneous...

1. Therapeutic anticoagulation with rivaroxaban or enoxaparin did not improve clinical outcomes and increased bleeding compared with prophylactic anticoagulation. 2. Net clinical benefit composite of death, thrombotic events, and major or clinically relevant non-major bleeding was not significantly different between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: COVID-19 is associated with...

1. Guided selection of antiplatelet therapy reduced rates of major adverse cardiovascular event rates compared to standard therapy. 2. Guided selection strategy was beneficial for both escalation and de-escalation of standard therapy, balancing patient-dependent ischemic and bleeding risks.  Evidence Rating Level: 1 (Excellent) Study Rundown: Patients who undergo percutaneous coronary intervention (PCI)...

1. In this randomized controlled trial, cold snare polypectomy with continuous anticoagulation does not increase bleeding risk when compared to hot snare polypectomy with heparin bridging. 2. The cold snare polypectomy procedure had shorter procedure time per lesion and decreased length of hospital stays in comparison to hot snare polypectomy. Evidence...

Aspirin (ASA) continues to be used for the primary prevention of cardiovascular disease (CVD) in patients at increased risk, despite evidence consistently demonstrating little benefit in cardiovascular event reduction and increased bleeding risk. Accordingly, the American Heart Association and American College of Cardiology (AHA/ACC) released new guidelines recommending against...

1. In this randomized controlled trial, cold snare polypectomy with continuous anticoagulation does not increase bleeding risk when compared to hot snare polypectomy with heparin bridging. 2. The cold snare polypectomy procedure had shorter procedure time per lesion and decreased length of hospital stays in comparison to hot snare polypectomy. Evidence...