Tag: blood pressure

1. In this secondary analysis of the Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT), lisinopril was associated with decreased incidence of conduction system disease when compared with the other antihypertensive medications, amlodipine and chlorthalidone. 2. Clinical factors associated with increased risk of conduction system disease included increased...
  Effect of Clopidogrel and Aspirin vs. Aspirin Alone on Migraine Headaches After Transcatheter Atrial Septal Defect Closure: The CANOA Randomized Clinical Trial New-onset migraines affect approximately 15% of patients that have undergone transcatheter atrial septal defect (ASD) closure. Following the transcatheter procedure, empirical antithrombotic therapy is indicated, with aspirin over...
  1. In this systematic review and meta-analysis of randomized controlled trials, more intensive treatment to lower systolic blood pressure below the currently recommended goal of 140 mmHg significantly reduced the risk of major cardiovascular events, myocardial infarction, stroke, retinopathy progression, and albuminuria, compared to less intensive treatment. 2. Trials in...
1. Based on Veterans Affairs primary care data on older adults with longstanding diabetes, deintensification of hypertension therapy, not including angiotensin converting enzyme inhibitors (ACE-I) amongst patients with moderately low and very low blood pressures (BP) occurred less than 20% of the time. 2. Similarly, deintensification of diabetes therapy, not...
1. Greater severity of weight class in pediatric patients associated with higher risk ratios of cardiometabolic risk factors including systolic and diastolic blood pressure (BP), HbA1c and triglycerides.  2. Male participants in higher obesity classes more likely to show significant differences in cardiometabolic risk factors, compared to female participants Evidence Rating:...
1. Vitamin D deficiency is associated with high blood pressure and cardiovascular disease. 2. Ameliorating vitamin D deficiency through supplementation did not lower blood pressure in this study. Evidence Rating Level: 1 (Excellent) Study Rundown: Previous work has demonstrated that low serum levels of vitamin D are associated with elevated blood pressure....
1. Blood pressure lowering in patients with diabetes mellitus type II was associated with a decreased risk of macro- and micro-vascular disease, as well as all-cause mortality. 2. Achieving a systolic BP <130 mmHg was associated with reduced risk of stroke, retinopathy, and albuminuria, with the reduction in risk greatest...
1. There was no significant difference between tight blood pressure control and less-tight control during pregnancy in terms of pregnancy loss, serious neonatal complications, or serious maternal complications. 2. There was a significantly higher rate of severe hypertension (≥160/110 mmHg) in the less-tight blood pressure control group, though this did...
1. Pediatric patients with moderate to severe atopic dermatitis (AD) were more likely to have an elevated body-mass index (BMI) for their age and sex reference range than patients without the disease. 2. Severe AD in pediatric patients was associated with elevated systolic blood pressure. Evidence Rating Level: 2 (Good) Study...
1. For ambulatory systolic blood pressure measurements, an increase of 10 mmHg was linked to an increased risk of stroke and cardiovascular events. Evidence Rating Level: 1 (Excellent) Study Rundown: Hypertension, blood pressure higher than 140 mmHg systolic and 90 mmHg diastolic, is a leading risk factor for mortality, but the...