Tag: Breast Cancer

Image: PD 1. The risk of a major coronary event in women treated with radiotherapy for breast cancer increases linearly with the mean dose of radiation to the heart at 7.4% per gray, with no apparent threshold below which there is no risk. 2. Women with ischemic heart disease risk factors,...
Feb 26th – The incidence of advanced breast cancer in women ages 25-39 has increased from 1.53/100,00 in 1976 to 2.90/100,000 in 2009. Image: PD 1. The incidence of advanced breast cancer in women ages 25-39 has increased from 1.53/100,00 in 1976 to 2.90/100,000 in 2009. 2. The increase was statistically significant...
Image: PD 1. Breast-conserving therapy (BCT) is associated with greater overall and disease-specific survival benefit than mastectomy for early-stage breast cancer, regardless of age and tumor hormone receptor status. 2. The benefit of BCT is greatest for women older than 50 years with HR-positive disease. Among breast cancer treatment options, there has...
Jan 26th - There is great variation in how knowledge of breast cancer overdiagnosis affects patient attitudes about screening and treatment. Image: PD 1. There is great variation in how knowledge of breast cancer overdiagnosis affects patient attitudes about screening and treatment. 2. Many women viewed up to 30% risk of...
Image: CC Key findings: 1.       Trastuzumab emtansine (T-DM1), an antibody-drug conjugate, prolonged disease-free survival compared to lapatinib plus capecitabine in HER2-positive breast cancer. 2.       T-DM1 had less severe toxicity than lapatinib plus capecitabine. Primer: A monoclonal antibody against human epidermal growth factor receptor 2 (HER2), trastuzumab (Herceptin), prevents progression and increases overall survival...