Tag: Breast Cancer

Association between incidence exposure to benzodiazepines in early pregnancy and risk of spontaneous abortion Previous studies have shown that benzodiazepine use in early pregnancy is associated with spontaneous abortion (SA). The association between specific benzodiazepines and the risk of SA, however, has not been investigated. In this nested case-control study...
1. A randomized control trial of patients with hormone receptor-positive metastatic breast cancer compared survival outcomes between patients who received combined anastrozole and fulvestrant therapy versus those receiving anastrozole alone, concluded that the combined therapy led to improved disease progression-free survival and overall survival rates. 2. There were no significant...
1. A randomized control trial of patients with hormone receptor-positive metastatic breast cancer compared survival outcomes between patients who received combined anastrozole and fulvestrant therapy versus those receiving anastrozole alone, concluded that the combined therapy led to improved disease progression-free survival and overall survival rates. 2. There were no significant...
For breast cancer patients, determining the risk of developing distant metastasis continues to present as a challenge, as the precise mechanism leading to distant metastasis is not yet fully understood. There has been a recent effort to develop imaging markers that can help predict patient prognosis, and therefore assist...
1. In this large observational cohort study, screening ultrasonography with mammography was not associated with an improvement in cancer detection rates over mammography alone. 2. Positive predictive value of biopsy recommendation was significantly lower with screening ultrasonography plus mammography compared with mammography alone. Evidence Rating Level: 2 (Good) Study Rundown: Breast cancer...
Association Between the Development of Pediatric Voice Disorders and Singing in Children’s Choir Singing has been thought to be protective against the development of voice disorders in children; however, there have been few studies evaluating this. In this cohort study, investigators analyzed data from 752 singing and 743 non-singing children...
The use of digital breast tomosynthesis (DBT) has been associated with increases in specificity and breast cancer detection compared with digital mammography (DM) alone. However, most published studies employed data from first- or prevalent-round screening rather than incident-round screening. In addition, few studies contained data such as age, breast...
1. Patients with residual human epidermal growth factor receptor 2 (HER2)-positive breast cancer after chemotherapy and HER2 targeted therapy had higher disease-free survival if treated with trastuzumab emtansine as opposed to trastuzumab alone. 2. More adverse events and serious adverse events occurred in patients treated with trastuzumab emtansine. Evidence Rating Level:...
Breast-conserving surgery or mastectomy followed by radiotherapy is commonly used in the treatment of early-stage breast cancer. There is growing interest in delivering postmastectomy radiotherapy with hypofractionated schedules to reduce cost and enable the treatment of more patients. However, the efficacy and safety of this approach has not yet...
Impact of scribes on emergency medicine doctors’ productivity and patient throughput: multicentre randomised trial Medical scribes are used in variety of clinical settings to complete clerical tasks otherwise done by a clinician. Limited research has been done concerning the effects of scribes on physician productivity in emergency medicine settings. In...