Schrödinger Halts CDC7 Inhibitor After Two Patient Deaths
Key Points: 1. Schrödinger discontinued its SGR-2921 CDC7 inhibitor program following two treatment-related deaths in a Phase 1 trial. 2. ...
Tag: cancer
Talazoparib and enzalutamide improve survival in metastatic castration-resistant prostate cancer
1. Progression-free survival and overall survival were significantly greater in the combination therapy group compared to enzalutamide alone. 2. Anemia ...
mFOLFIRINOX may have a limited role in pancreatic cancer in Phase II/III trial
1. In patients with metastatic pancreatic cancer, neither modified fluorouracil, leucovorin, irinotecan and oxaliplatin (mFOLFIRINOX) or S-1, irinotecan and oxaliplatin ...
Randomized Phase III trial of Ramucirumab finds benefit for patients with refractory advanced gastric cancer
1. The addition of ramucirumab to irinotecan in patients with ramucirumab-refractory advanced or recurrent gastric or gastroesophageal cancer (AGC) did ...
Increased Serum 25(OH)D levels associated with decreased mortality risk in adult men
1. Increases in serum 25 (OH) D concentration were nonlinearly associated with decreased all-cause, cardiovascular disease mortality, and cancer mortality, ...
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2MM: AI Roundup – Pancreatic Cancer Prediction Breakthrough, Retinal Stroke Risk Maps, Microsoft’s MAI‑DxO Diagnostic Upset, and Kenya’s AI Consult Real‑World Win [July 28th, 2025]
AI scans detect pancreatic cancer years before symptoms emerge A new deep learning model may have cracked one of ...
Relacorilant plus nab-paclitaxel improves survival in platinum-resistant ovarian cancer patients
1. Progression-free and overall survival were greater in relacorilant plus nab-paclitaxel compared to nab-paclitaxel alone. 2. The rate of adverse ...
The Scan by 2 Minute Medicine®: Shoulder scalpel, shark scare, Alzheimer dosing tweak, and a Blenrep blow
The Scan by 2 Minute Medicine® is a pop-culture medical newsletter and exclusive benefit for 2 Minute Medicine Plus subscribers. Will ...
Minimally invasive surgery is beneficial for epithelial ovarian cancer
1. Conducting phase 3 of the Laparoscopic Cytoreduction After Neoadjuvant Chemotherapy (LANCE) trial is feasible, as evidenced by an adequate ...
2MM: AI Roundup – FDA’s AI Push, Trial Speedups with Real-World Data, Smart Surgical Monitors, and Regulatory Overhaul Begins [July 2nd, 2025]
Epic Launchpad propels generative AI into everyday hospital routines Epic Systems quietly rolled out Launchpad earlier this month, handing health systems a ...
