Tag: carotid stenosis

1. Absolute risk reduction of stroke in asymptomatic carotid stenosis was significantly lower than it was two decades ago. 2. Advances in stroke prevention suggest that medical therapy may be an acceptable treatment strategy for this population. Evidence Rating Level: 2 (Good) Carotid endarterectomy (CEA) has been shown effective in both asymptomatic...
Migraines During Pregnancy and the Risk of Maternal Stroke 1. Women with migraines are at an increased risk of stroke during and after pregnancy compared to those without migraines. Evidence Rating Level: 2 (Good) Increased risk of maternal stroke is associated with migraines during the perinatal period, with the belief that...
1. In patients receiving carotid stenosis treatment, transcarotid artery revascularization was associated with a significantly lower risk of stroke or death compared to transfemoral carotid artery stenting. Evidence Rating Level:2 (Good) Study Rundown: Transfemoral carotid artery stenting has served as an alternative approach to the standard of care, for patients requiring...
Risk Prediction Tools to Improve Patient Selection for Carotid Endarterectomy Among Patients with Asymptomatic Carotid Stenosis Carotid endarterectomy (CEA) is an effective tool for revascularization in patients with carotid artery stenosis. However, in the setting of asymptomatic stenosis, careful risk-benefit analysis is needed in determining whether the long-term benefits of...
An Evaluation of the Effects of Lowering Blood Alcohol Concentration Limits for Drivers on the Rates of Road Traffic Accidents and Alcohol Consumption: A Natural Experiment Individuals that drive while under the influence of alcohol are at an increased risk of being involved in traffic accidents, contributing to the morbidity...
1. In this analysis of treatment patterns in the United States for the years prior to, and following, the Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST), the use of carotid artery stenting (CAS) rose amongst patients 70 years and older despite the evidence for worse outcomes. 2. The increase in...
1. There were no significant differences between stenting versus carotid endarterectomy (CEA) for patients with carotid stenosis (symptomatic or asymptomatic) with regards to the risk of periprocedural stroke, MI, or death and subsequent ipsilateral stroke.  Evidence Rating Level: 1 (Excellent)       Study Rundown: The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) had...
1. There was no significant difference between stenting versus carotid endarterectomy (CEA) for asymptomatic patients with carotid stenosis that were not at high risk for post-operative complications. 2. The study was discontinued prior to it reaching the number needed for 80% certainty due to the extended period of time...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Goal-Directed Resuscitation for Patients with Early Septic Shock The monumental Rivers et al publication laid forth the groundwork for early goal-directed therapy (EGDT) for sepsis management, a framework that has been embraced...
Classics Series, Landmark Trials in Medicine
1. Dual antiplatelet therapy with clopidogrel and aspirin was associated with a significant reduction in microembolic events in patients with symptomatic carotid stenosis compared to aspirin alone 2. There was no significant difference between the two groups in the risk of bleeding Original Date of Publication: May 3, 2005  Study Rundown: The...