Tag: chemoradiotherapy

1. Adjuvant capecitabine resulted in fewer instances of disease recurrence and death compared to standard therapy. 2. Overall and failure-free survival at 3 years was significantly greater in the capecitabine group. Evidence Rating Level: 1 (Excellent) Study Rundown: Nasopharyngeal carcinoma is a form of invasive head and neck cancer with a favorable...
1. Although combining pembrolizumab to chemoradiotherapy as part of total neoadjuvant therapy after FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin) treatment was safe overall, the difference in neoadjuvant rectal score does not support further study of this novel combination for the treatment of locally advanced rectal cancer. 2. These results and the...
1. Neoadjuvant chemoradiotherapy (NCRT) with surgery improves the death rate, overall survival, disease-free survival time, and locoregional and distal recurrence rates of advanced esophageal squamous cell carcinoma compared to surgery alone 2. While NCRT incurred more adverse events, there was not more treatment-associated deaths, thus the survival benefit could potentially...
1. Primary treatment with chemoradiotherapy when treating oropharyngeal squamous cell carcinoma had improved progression-free survival and distant metastasis-free survival compared to when treated with upfront surgery. 2. There was no significant difference in mortality during the study period in the upfront surgical treatment versus chemoradiotherapy groups. Evidence Rating Level: 2 (Good) Study...