Tag: Chlorhexidine

Universal decontamination in the intensive care unit (ICU) has led to success in reducing bloodstream infections and infections with multi-drug resistant organisms. In this cluster-randomized trial of 53 hospitals, a similar protocol of universal decontamination using daily chlorhexidine bathing, as well as the administration of muciprocin for known methicillin-resistant...
Veverimer Versus Placebo in Patients with Metabolic Acidosis Associated with Chronic Kidney Disease: a Multicenter, Randomized, Double-Blind, Controlled, Phase 3 Trial Chronic metabolic acidosis is often seen in patients with chronic kidney disease (CKD), and results from an inability to excrete metabolically produced acid. This, in turn, is associated with...
1. In this study, daily bathing with chlorhexidine did not decrease the rates of hospital-acquired infections in ICU patients. 2. The hospital-acquired infections that were assessed in this study included central line associated blood stream infections (CLABSI), catheter-associated urinary tract infections (CAUTI), ventilator associated pneumonia (VAP), and C. difficile infections. Evidence...
Image: PD  1. A significant decrease in lower respiratory tract infections was noted in cardiac-surgery patients with the use of chlorhexidine.  2. Although there was no decrease in mortality noted with the use of chlorhexidine in cardiac-surgery or non-cardiac surgery studies, there was a non-significant increase in mortality in the non-cardiac...
Image: PD 1. Umbilical separation time is prolonged by 2-3 days with chlorhexidine cleansing as compared to dry and clean care.  2. Prolonged umbilical separation time did not significantly increase risk of omphalitis. 3. Although parents were aware of and displeased with the increased separation time in the chlorhexidine group, there...
Feb 6th - NEJM - Daily bathing with a chlorhexidine-impregnated washcloth was associated with a 28% lower rate of bloodstream infections.  Image: PD 1. Daily bathing with a chlorhexidine-impregnated washcloth was associated with a 28% lower rate of bloodstream infections when compared with daily washing with a nonantimicrobial washcloth. 2. Chlorhexidine bathing...