Tag: congestive heart failure
IV ferric carboxymaltose reduces risk of heart failure hospitalizations in patients with iron-deficiency and acute heart failure
Vineeth Bhogadi -0
1. Treatment with IV ferric carboxymaltose reduced the risk of heart failure hospitalizations in patients with iron deficiency and acute heart failure with a left ventricular ejection fraction less than 50%.
2. IV ferric carboxymaltose was generally safe but had no significant effect on the risk of cardiovascular death compared...
#VisualAbstract: Burden and Causes of Hospital Admissions in Heart Failure During the Last Year of Life
Ravi Shah, MD MBA -
1. In this retrospective analysis of patients with heart failure, admissions to the hospital for non-cardiac problems were more frequent than admissions for heart failure or cardiovascular (CV) disease.
2. The frequency of hospital admissions increased towards the time of death but without change in proportion of admissions for heart...
Non-cardiac admissions most common for heart-failure patients in last year of life
James England, MD -
1. In this retrospective analysis of patients with heart failure, admissions to the hospital for non-cardiac problems were more frequent than admissions for heart failure or cardiovascular (CV) disease.
2. The frequency of hospital admissions increased towards the time of death but without change in proportion of admissions for heart...
Beneficiaries of Medicare Advantage run higher risk of readmission compared with traditional Medicare
Caitlyn Hui -
1. In this retrospective cohort study, the authors observed that Medicare Advantage beneficiaries have a higher risk of readmission compared to traditional Medicare in with regards to congestive heart failure, pneumonia and acute myocardial infarction.
2. There were higher readmission rates for Medicare Advantage beneficiaries compared to traditional Medicare beneficiaries...
Centrifugal-flow pumps improve complication free survival compared to axial flow-pumps: The MOMENTUM 3 trial
Shani Chibber -
1. Advanced heart failure patients randomized to receive centrifugal-flow pumps demonstrated higher rates of 2-year survival free of disabling stroke or reoperation to remove or replace their device compared to patients randomized to receive axial-flow pumps.
2. There were also lower rates of pump thrombosis among patients assigned to the...
Hemodynamic markers of pulmonary hypertension in heart failure with preserved ejection fraction are associated with mortality
Angela Zhang -
1. Pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF) is common in patients undergoing a right heart catheterization.
2. Transpulmonary gradient (TPG), pulmonary vascular resistance (PVR), and diastolic pulmonary gradient (DPG) are predictors of mortality and cardiac hospitalizations in PH-HFpEF.
Evidence Rating Level: 2 (Good)
Study Rundown: Pulmonary hypertension...
Collaborative care intervention does not improve health in chronic heart failure, but alleviates depression and fatigue
Angela Zhang -
1. Collaborative Care to Alleviate Symptoms and Adjust to Illness (CASA), a collaborative care intervention combining symptom and psychosocial care, did not improve heart failure-specific health status in chronic heart disease, compared to usual care.
2. When compared to usual care, CASA did improve secondary outcomes of depression and fatigue.
Evidence...
Shared decision making intervention linked to improved value/treatment choice concordance in LVAD destination therapy
James England, MD -
1. In this randomized, stepped-wedge control trial of patients with heart failure under consideration for mechanical circulatory support (MCS), a shared decision-making educational intervention was linked with improved patient comprehension of left ventricular assist devices (LVAD) and concordance of treatment choice with patient values.
2. The shared decision making intervention...
The PARADIGM-HF trial: Valsartan-neprilysin inhibitor vs. enalapril in patients with heart failure [Classic Series]
Shaidah Deghan, MSc. -
1. LCZ696, a combination of valsartan with a neprilysin inhibitor, significantly reduced the risk of death from cardiovascular causes and hospitalization due to heart failure when compared to enalapril.
2. There were no significant differences between the two groups in the risk of angioedema, though patients treated with LCZ696 experienced...
Outcomes after left ventricular assist device implantation significantly worse for those with end-stage renal disease
James England, MD -
1. Patients with end-stage renal disease (ESRD) have significantly worse survival outcomes following left ventricular assist device (LVAD) implantation compared to recipients without ESRD.
2. The median time to death was substantially shorter in those with ESRD, with many patients dying during the index hospitalization.
Evidence Rating Level: 2 (Good)
Study Rundown:...