Tag: contraception

Previous studies have suggested that certain hormonal contraceptive methods, including intramuscular depot medroxyprogesterone acetate (DMPA-IM), may increase women’s susceptibility to HIV acquisition. In this randomized, open-label trial, 7829 women living in areas of high HIV incidence in Africa were randomly assigned to receive DMPA-IM (n=2609), a copper intrauterine device...
1. A total of 1 in 5 women in the US reported delayed contraceptive initiation (>1 month after sexual debut), with higher rates of delayed use reported among African American, Hispanic, or low-income women. 2. Delayed contraceptive initiation was associated with an almost 4 times higher risk of unintended pregnancy...
1. Müllerian inhibiting substance (MIS) was found to be a successful and safe contraceptive in female mice. 2. Female mice administered MIS during chemotherapy exhibited higher numbers of ovarian follicles. Evidence Rating Level: 1 (Excellent) Study Rundown: Currently, MIS levels are clinically measured to determine the follicular reserve of the ovaries. This...
1. Adoption of any contraceptive method among non-users was associated with a greater reduction in unintended pregnancy rate than adoption of LARC among women using a less effective method. 2. Among current contraceptive users, adoption of long-acting reversible contraception (LARC) was associated with a decrease in unintended pregnancy rate. Evidence Rating...
1. In this unmatched case-control study, risk of cerebral venous thrombosis (CVT) amongst women on oral contraceptives increased in a dose-dependent manner depending on their BMI category (normal, overweight, or obese). 2. There was no statistically significant association between BMI and CVT in males or in women who did not...
1. Previous pregnancies, age <35 years and increasing proportion of sex acts without protection were predictive of incidental pregnancy. 2. A risk scoring tool demonstrated excellent negative predictive value for unintended pregnancy. Evidence Rating Level: 1 (Excellent)       Study Rundown: Unintended pregnancies comprise about half of all pregnancies in the United States. While...
1. Women taking newer formulations of combined oral contraceptive pills, with the exception of norgestimate, were more likely to have had a blood clot than those using second-generation drugs. 2. The absolute risk of blood clot remained low, with just 14 additional cases per 10 000 women per year. Evidence Rating...
1. Family planning providers were nearly four times more likely to use long-acting reversible contraception than women in the general population. 2. Providers were more likely to use intrauterine contraception, the vaginal ring and implants and less likely to use female sterilization and condoms. Evidence Rating Level: 3 (Average)       ...
1. Contraceptive implants and hormonal intrauterine devices (IUDs) remained highly effective for four and six years respectively, one year beyond their FDA approved duration of use. 2. In contraceptive implant users, serum hormone levels were adequate for ovulation suppression even after four years of use and did not vary by BMI. Evidence...
1. Most patients in a dermatology clinic had gaps in their baseline knowledge of contraceptive effectiveness and overestimated the typical effectiveness of condoms, oral contraceptives, and contraceptive injections. 2. After viewing an information sheet on effectiveness of various contraceptive options, patients significantly improved their contraceptive knowledge. Evidence Rating Level: 2...