Tag: corticosteroid

1. In patients with mild asthma, use of the inhaled combined corticosteroid (ICS) and beta agonist budesonide-formoterol as needed was superior to terbutaline as needed with respect to electronically recorded weeks of well-controlled asthma. 2. While budesonide-formoterol as needed was inferior to twice daily budesonide maintenance therapy with respect to...
1. In this meta-analysis of available comparative studies, use of corticosteroids as adjunctive therapy to IVIG and aspirin in Kawasaki disease was associated with a lower risk of coronary artery abnormality and earlier defervescence compared to IVIG/ASA alone. 2. In subgroup analysis the earlier timing of steroid therapy had lower...
Classics Series, Landmark Trials in Medicine
1. Compared to placebo, treating patients with severe alcoholic hepatitis with 28 days of prednisolone significantly improved the short-term survival up to 6 months. 2. There remains significant controversy surrounding the use of glucocorticoids in managing severe alcoholic hepatitis, as numerous other trials have demonstrated no mortality benefit, but significantly...
1. Use of acute corticosteroids versus placebo in patients with severe community-acquired pneumonia (CAP) and a high initial inflammatory response resulted in a decrease in treatment failure. 2. There was no statistically significant difference in in-hospital mortality between the two groups. Evidence Rating Level: 1 (Excellent) Study Rundown: The mortality of patients...