Tag: diabetes

1. Older adults with prediabetes were more likely to regress to normoglycemia or pass away than progress to diabetes. 2. Prediabetes may be a weak indicator of risk for diabetes among older adults. Evidence Rating Level: 2 (Good) Prediabetes is known as a risk factor for progression to diabetes, often used to...

1. Compared to patients of European descent, poorer health outcomes were seen among Māori and Pacific New Zealanders with type 2 diabetes. 2. Māori patients had the highest incidence rate of all-cause mortality, cardiovascular mortality, and cancer mortality. Evidence Rating Level: 2 (Good) Study Rundown: Disparities associated with ethnicity and socioeconomic status...

1. 10-year remission rates were significantly higher for Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion (BPD) than medical therapy. 2. Patients in the BPD and RYGB groups had fewer diabetes-related complications.  Evidence Rating Level: 1 (Excellent) Study Rundown: Compared to conventional therapy, metabolic surgery results in significant short-term improvements among patients with...

1. Participants using the novel advanced hybrid insulin delivery system (Medtronic) had a greater proportion of time spent in their target glucose range versus control. 2. Proportion of time spent in hypoglycemic ranges was non-inferior between the Medtronic and control groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Although various technological advances...

1. Participants using the novel advanced hybrid insulin delivery system (Medtronic) had a greater proportion of time spent in their target glucose range versus control. 2. Proportion of time spent in hypoglycemic ranges was non-inferior between the Medtronic and control groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Although various technological advances...

1. Significant gaps were found in the use of evidence-based therapies in insured patients with atherosclerotic cardiovascular disease and type 2 diabetes mellitus. Evidence Rating Level: 2 (Good) Prevalence of atherosclerotic cardiovascular disease (ASCVD) in patients with type 2 diabetes mellitus (T2DM) is twice as high as those without T2DM, resulting...

1. Persistently high fasting insulin levels were associated with psychosis and psychotic disorder later in life. 2. Major increases in body mass index during puberty were associated with increased risk of depression later in life, but not psychosis. Evidence Rating Level: 2 (Good) Cardiometabolic disorders often co-occur with schizophrenia and depression, which...

1. Sotagliflozin was shown to lower the risk of total number of deaths from cardiovascular causes and hospitalizations and urgent visits for heart failure in patients with diabetes and recent worsening heart failure compared to placebo. 2. Sotagliflozin was shown to be similar in the percentage of patients with adverse...

1. In-home glucose-lowering medications were not associated with increased mortality or complications among those with COVID-19. Evidence Rating Level: 2 (Good) Diabetes is one of the most common comorbidities found among patients with coronavirus disease 2019 (COVID-19), with type 2 diabetes mellitus (T2DM) negatively impacting prognosis in these people. The potential...

1. Increased levels of circulating ACE2 were associated with greater risk of cardiovascular and non-cardiovascular death, heart failure, myocardial infarction, stroke, and diabetes. 2. Compared to other clinical risk factors such as diabetes, body-mass index, smoking status, non-HDL cholesterol, and systolic blood pressure, plasma ACE2 was the strongest predictor...